Evidence map›Paper›PMID 40754911›Full record

ArticleBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2025

[Protective effect of knock-down the expression of

Q Qin, R Li, Y Zhou, Y Zhang, M Han, L Zhu

Abstract readEnglish Abstract
In one paragraph

Article in Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Q QinPeking University Ditan Teaching Hospital, Beijing 100015, China.
R LiBeijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Y ZhouBeijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
Y ZhangBeijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
M HanBeijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.
L ZhuPeking University Ditan Teaching Hospital, Beijing 100015, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the protective effect of knock-down the expression of B lymphocyte induced maturation protein 1 (

methodsC57BL/6 mice were intraderitoneal injected with 5% CCl

resultsThe expression levels of Blimp1 protein in the liver of CCl

conclusionBlimp1 plays an important role in CCl

Indexed as

Liver CirrhosisTranscription FactorsActinsAnimalsCarbon TetrachlorideDependovirusDisease Models, AnimalGene Knockdown TechniquesLiverMaleMiceMice, Inbred C57BLPositive Regulatory Domain I-Binding Factor 1RNA, Small InterferingActinsCarbon TetrachloridePositive Regulatory Domain I-Binding Factor 1Prdm1 protein, mouseRNA, Small InterferingTranscription FactorsAnimal modelsB lymphocyte induced maturation protein 1Liver fibrosisLiver injury

Identifiers

PMID40754911
PMCPMC12330913

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.