Evidence map›Paper›PMID 40754879›Full record

ReviewCurrent drug delivery2026

Applications of Biodegradable Polymeric Nanomaterials as Drug Delivery Systems.

Han Bao, Ning Wang, Jia Guo, Xiangjun Han

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current drug delivery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Han BaoDepartment of Interventional Radiology, The First Hospital of China Medical University, Shenyang 110001, China.ORCID 0000-0002-1972-2148
Ning WangDepartment of Radiology, Shengjing Hospital of China Medical University, Shenyang 110004, China.
Jia GuoDepartment of Ultrasound, Shengjing Hospital of China Medical University, Shenyang 110004, China.
Xiangjun HanDepartment of Interventional Radiology, The First Hospital of China Medical University, Shenyang 110001, China.ORCID 0000-0003-1931-9065

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are a variety of biodegradable polymers, including natural polysaccharides, proteins, nucleic acids, etc., in animals and plants, as well as some polymers that are synthesized by microorganisms, such as poly(3-hydroxybutyrate-co-3-hydroxyhexanoate). At present, the most common polymers are those that are artificially synthesized, such as polyethylene glycol, polylactic acid, and polycaprolactone. These polymers can degrade via hydrolytic and enzymatic processes in the body into low-molecular-weight products that are then reabsorbed or excreted, making them the most suitable materials for the synthesis of biodegradable nanoparticles. Biodegradable polymers can react with other substances to form nanocomposites, which have superior biocompatibility, degradability, and safety. Biodegradable polymer-based nanocomposites exhibit targeting capabilities, including passive (enhanced permeability and retention effect), active (ligand-receptor interactions), tumor microenvironment-responsive, and external stimulus-responsive (e.g., magnetic, electric, and lightdriven) targeting. In addition, synthesized biodegradable nanomaterials can alter the solubility of the loaded drug and improve its bioavailability. Thus, these materials have been widely used in drug delivery systems. This review aimed to summarize the recent advances in biodegradable polymeric nanomaterials for biomedical drug delivery, analyze their design advantages and clinical translation potential, and explore their future prospects and challenges in precision therapy and targeted delivery.

Indexed as

Drug Delivery SystemsNanostructuresPolymersAnimalsHumansPolymersapplicationBiodegradable polymersdrug deliverymolecular imagingnanoparticlestargeting therapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.