Evidence map›Paper›PMID 40754583›Full record

ReviewMilitary Medical Research2025

Artificial intelligence in orthopedics: fundamentals, current applications, and future perspectives.

Jian Song, Guang-Chao Wang, Si-Cheng Wang, Chong-Ru He, Ying-Ze Zhang, Xiao Chen, Jia-Can Su

Abstract readReview
In one paragraph

Review in Military Medical Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  7. Trend of Myopia Incidence Among Adolescents (2018-2025) in Senior High School: An 8-Year Retrospective Study in Multi-Regions of China, With Projections to 2030.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
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  15. [Advances in application of digital orthopedic technology in total hip arthroplasty for developmental dysplasia of hip].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jian Song *Department of Orthopedics, Trauma Orthopedics Center, Institute of Musculoskeletal Injury and Translational Medicine of Organoids, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Guang-Chao Wang *Department of Orthopedics, Trauma Orthopedics Center, Institute of Musculoskeletal Injury and Translational Medicine of Organoids, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Si-Cheng Wang *Department of Orthopedics, Shanghai Zhongye Hospital, Shanghai, 200941, China.
Chong-Ru HeDepartment of Orthopedics, Trauma Orthopedics Center, Institute of Musculoskeletal Injury and Translational Medicine of Organoids, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Ying-Ze ZhangDepartment of Orthopedics, Orthopedic Research Institution of Hebei Province, NHC Key Laboratory of Intelligent Orthopedic Equipment, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China. yzzhang@hebmu.edu.cn.
Xiao ChenDepartment of Orthopedics, Trauma Orthopedics Center, Institute of Musculoskeletal Injury and Translational Medicine of Organoids, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. sirchenxiao@sjtu.edu.cn.
Jia-Can SuDepartment of Orthopedics, Trauma Orthopedics Center, Institute of Musculoskeletal Injury and Translational Medicine of Organoids, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. drsujiacan@163.com.ORCID 0000-0001-7080-263X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional diagnostic and therapeutic approaches in orthopedics are frequently time intensive and associated with elevated rates of diagnostic error, underscoring the urgent need for more efficient tools to improve the current situation. Recently, artificial intelligence (AI) has been increasingly integrated into orthopedic practice, providing data-driven approaches to support diagnostic and therapeutic processes. With the continuous advancement of AI technologies and their incorporation into routine orthopedic workflows, a comprehensive understanding of AI principles and their clinical applications has become increasingly essential. The review commences with a summary of the core concepts and historical evolution of AI, followed by an examination of machine learning and deep learning frameworks designed for orthopedic clinical and research applications. We then explore various AI-based applications in orthopedics, including image analysis, disease diagnosis, and treatment approaches such as surgical assistance, drug development, rehabilitation support, and personalized therapy. These applications are designed to help researchers and clinicians gain a deeper understanding of the current applications of AI in orthopedics. The review also highlights key challenges and limitations that affect the practical use of AI, such as data quality, model generalizability, and clinical validation. Finally, we discuss possible future directions for improving AI technologies and promoting their safe and effective integration into orthopedic care.

Indexed as

Artificial IntelligenceOrthopedicsDeep LearningHumansMachine LearningArtificial intelligence (AI)Deep learning (DL)DiagnosticMachine learning (ML)OrthopedicsTherapeutics

Identifiers

PMID40754583
PMCPMC12320344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.