Evidence map›Paper›PMID 40754571›Full record

ArticleClinical breast cancer2026

Examining the Interrelationships of Lymphedema with Pain, Physical Function, and Demographic and Medical Variables in Women with Breast Cancer and Pain.

Grace H Amaden, Kelly A Hyland, Joseph G Winger, Sarah A Kelleher, Allison K Diachina, Shannon N Miller, Kelly Westbrook, Gretchen Kimmick, Linda Sutton, Mei R Fu and 1 more

Abstract read
In one paragraph

Article in Clinical breast cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Grace H AmadenDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC.
Kelly A HylandDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC.
Joseph G WingerDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC; Duke Cancer Institute, Duke University, Durham, NC.
Sarah A KelleherDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC; Duke Cancer Institute, Duke University, Durham, NC.
Allison K DiachinaDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC.
Shannon N MillerDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC.
Kelly WestbrookDuke Cancer Institute, Duke University, Durham, NC.
Gretchen KimmickDuke Cancer Institute, Duke University, Durham, NC.
Linda SuttonDuke Cancer Institute, Duke University, Durham, NC.
Mei R FuUniversity of Missouri-Kansas City, Kansas City, MO.
Tamara J SomersDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC; Duke Cancer Institute, Duke University, Durham, NC. Electronic address: Tamara.somers@duke.edu.

Funding

Optimizing Delivery of a Behavioral Cancer Pain Intervention Using a SMARTR01CA202779 · NCI · DUKE UNIVERSITY · PI SOMERS, TAMARA J · 2016 to 2020
$2.8M
NCI NIH HHS R01 CA202779
6 · The paper itself

Abstract

purposeTo examine the relationship of lymphedema with pain, physical function, and demographic and medical variables in women with breast cancer and pain.

methodsSecondary analysis of baseline data from a study of women with breast cancer and pain. Self-report questionnaires assessed lymphedema, pain severity, pain medication use behavior, pain-related cognitions (ie, pain self-efficacy, pain catastrophizing), and physical function (ie, basic and intermediate activities of daily living (ADLs)). Demographic and medical variables were extracted from the medical record. Univariate analyses examined relationships among lymphedema and variables of interest.

resultsWomen (N = 327, M

conclusionIn women with breast cancer and moderate pain, lymphedema is associated with greater pain severity and pain catastrophizing, and decreased ability to complete intermediate ADLs. Women with lymphedema and pain may benefit from tailored, accessible cognitive-behavioral-physiological interventions to improve self-management (eg, Pain Coping Skills Training, interventions to promote lymph flow and reduce inflammation). Disparities in lymphedema prevalence by race and education warrant further exploration.

Indexed as

Activities of Daily LivingBreast NeoplasmsCancer PainLymphedemaPainAdultAgedCatastrophizationFemaleHumansMiddle AgedPain MeasurementSelf EfficacySelf ReportSeverity of Illness IndexSurveys and QuestionnairesActivities of daily livingBreast cancer survivorPain catastrophizingPain self-efficacyPain severity

Identifiers

PMID40754571
PMCPMC12342047

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.