Evidence map›Paper›PMID 40754567›Full record

ArticleCell research2025

Structure and activation mechanism of human sweet taste receptor.

Haolan Wang, Xiao Chen, Yaxin Dai, Shabareesh Pidathala, Yiming Niu, Chen Zhao, Siyu Li, Liang Wang, Chia-Hsueh Lee

Abstract readLetter
In one paragraph

Article in Cell research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Molecular Dynamics Insights into TAS1R2 Transmembrane Domain Activation.International journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haolan Wang *Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Xiao Chen *Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Yaxin DaiDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0002-8983-5279
Shabareesh PidathalaDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0002-2998-4117
Yiming NiuLaboratory of Chromosome and Cell Biology, The Rockefeller University, New York, NY, USA.ORCID http://orcid.org/0000-0002-5683-1781
Chen ZhaoDepartment of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL, USA.ORCID http://orcid.org/0000-0002-2323-6951
Siyu LiDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Liang WangDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Chia-Hsueh LeeDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA. chiahsueh.lee@stjude.org.ORCID http://orcid.org/0000-0003-0819-6477

Funding

Structural and Functional Studies of Human Serine Palmitoyltransferase ComplexesR01GM143282 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI LEE, CHIA-HSUEH · 2021 to 2025
$1.8M
Structural and functional investigations on synaptic vesicular transportersR01NS133147 · NINDS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Chia-Hsueh Lee · 2024 to 2026
$1.6M
NIGMS NIH HHS R01 GM143282NINDS NIH HHS R01 NS133147
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40754567
PMCPMC12484785

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.