Evidence map›Paper›PMID 40754566›Full record

ArticleDigestive diseases and sciences2025

Knowledge, Attitudes, and Perceptions Around Colorectal Cancer Screening and Risk Among 20-49 Year Olds.

Timothy Yen, Paul C Schroy, Heather Hampel, Michelle Aubertine, Kaitlin Sylvester, Whitney Jones, Swati G Patel

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Article in Digestive diseases and sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Understanding the Impact of Psychosocial Barriers on Colorectal Cancer Knowledge in Emerging Adult Black Men.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Timothy YenDivision of Gastroenterology, Loma Linda University Health, Loma Linda, CA, USA.
Paul C SchroySection of Gastroenterology, Boston University School of Medicine, Boston, MA, USA.
Heather HampelDivision of Clinical Cancer Genomics, City of Hope, Duarte, CA, USA.
Michelle AubertineKS&R, Syracuse, NY, USA.
Kaitlin SylvesterNational Colorectal Cancer Roundtable, American Cancer Society, Atlanta, GA, USA.
Whitney JonesSchool of Public Health and Information Sciences, University of Louisville, Louisville, KY, USA.
Swati G PatelDivision of Gastroenterology, University of Colorado Anschutz Medical Center, 1635 Aurora Court, Aurora, CO, 80045, USA. Swati.Patel@cuanschutz.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe incidence of colorectal cancer (CRC) diagnosed before age 50 is rising. CRC screening rates are suboptimal, and there are substantial diagnostic delays among those with red flag symptoms. We aimed to assess the knowledge of blood in stool as a red flag for CRC, fear of screening procedures, and perceived trust in doctors among younger individuals, including associated factors.

methodsWe performed an analysis of a nationwide exploratory survey of 747 individuals 20-49 years old. We also assessed factors associated with knowledge of blood in stool as a red flag for CRC, fear of screening procedures, and perceived trust in doctors as representative questions from each domain of accurate knowledge, positive attitude, and trusted sources of health information, respectively, using multivariable logistic regression, with adjustment for false discovery rate.

results76% agreed that CRC screening should be performed, but only 16% were aware that CRC screening should start at age 45. 56% would ask their provider about CRC risk in the setting of rectal bleeding. Almost half of the participants feared CRC screening tests. Most participants trusted health information from medical providers (86%); less than 1/3 of participants trusted health information from news anchors (28.1%), celebrities (23.3%), social media Figs. (10.1%), and faith-based leaders (25.7%). Use of social networking sites (Odds Ratio 2.02, 95% Confidence Interval 1.41-2.89) was independently associated with accurate knowledge of blood in the stool as a red flag for CRC.

conclusionThere are still critical gaps in knowledge and intention toward CRC screening among 20-49 years old. Future research should focus on tailoring content, route, and sources of motivational education to improve screening in younger audiences.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerHealth Knowledge, Attitudes, PracticeMass ScreeningAdultFemaleHumansMaleMiddle AgedOccult BloodRisk FactorsTrustYoung AdultColorectal cancer screeningEarly-onset colorectal cancer

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.