ArticleThe American journal of clinical nutrition2025
Wild foods as drivers of blood ergothioneine and selenoneine concentrations among Inuit living in Nunavik: results from the cross-sectional Qanuilirpitaa? 2017 survey.
Article in The American journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Natural Histidine Derivatives-From Basic Research to Potential Applications in Cosmetics and Nutricosmetics.Antioxidants (Basel, Switzerland) · 2026Review
- Selenoneine and ergothioneine in beluga skin and tissues as key antioxidants in the Inuit diet.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWild foods traditionally harvested by Inuit, also called country foods, are potential sources of ergothioneine and selenoneine, 2 closely related antioxidants with potential health benefits.
objectiveTo determine concentrations of these compounds and methylated metabolites in blood samples from 1291 Nunavik residents (Nunavimmiut) aged ≥16 y who participated in the cross-sectional Qanuilirpitaa? 2017 Health Survey and associated dietary habits.
methodsBlood levels were measured using isotope dilution-liquid chromatography-tandem MS. Associations with dietary profiles or selected dietary habits (documented by a food frequency questionnaire) were investigated using multivariate models.
resultsGeometric mean concentrations (95% confidence interval [CI]) of ergothioneine, S-methyl-ergothioneine, selenoneine, and Se-methyl-selenoneine, were 92.5 mg/L (88.4, 96.8), 139 μg/L (133, 146), 355 μg/L (328, 385) and 11.6 μg/L (10.7, 12.5), respectively. Geometric mean ratios (GMR) (95% CI) comparing females with males were 1.27 (1.18, 1.39) and 1.82 (1.57, 2.11) for ergothioneine and selenoneine, respectively. GMR comparing ≥60 y olds to youth aged 16 to 19 y were 1.75 (1.52, 2.02) and 2.78 (2.04, 3.69) for ergothioneine and selenoneine, respectively. Blood selenoneine concentrations of Hudson Strait residents exceeded those of Ungava Bay (2.38 [1.97, 2.86]) and Hudson Bay residents (2.70 [2.22, 3.28]). GMR comparing the high-country food consumption profile with none (or very low) profile were 1.33 (1.10, 1.61) and 2.35 (1.65, 3.36) for ergothioneine and selenoneine, respectively. Country foods positively associated with ergothioneine concentrations included Arctic char (1.07 [1.04, 1.10]) and caribou meat (1.06 [1.03, 1.10]), whereas country foods positively linked to selenoneine concentrations comprised Arctic char (1.07 [1.02, 1.12]) and beluga mattaaq (1.15 [1.08, 1.22]).
conclusionsAlthough comparative data are limited, blood selenoneine and ergothioneine concentrations among Nunavimmiut appear substantially higher than in other non-Indigenous populations. Access to country food is important to maintain the dietary intake of these bioactive food components that may be beneficial for the health of Nunavimmiut.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.