Evidence map›Paper›PMID 40754054›Full record

ArticleJournal of neuroscience methods2025

A novel device for studying temperature and touch interactions.

Juan Carlos Ramirez, Jose Vergara, Jing Lin, Jian Chen, Jeffrey M Yau

Abstract read
In one paragraph

Article in Journal of neuroscience methods, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Illusory cold desensitizes touch.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Juan Carlos RamirezDepartment of Neuroscience, Baylor College of Medicine, Houston, TX 77030, United States; Baylor College of Medicine, Medical Scientist Training Program, Baylor College of Medicine, Houston, TX 77030, United States.
Jose VergaraDepartment of Neuroscience, Baylor College of Medicine, Houston, TX 77030, United States.
Jing LinDepartment of Neuroscience, Baylor College of Medicine, Houston, TX 77030, United States.
Jian ChenDepartment of Neuroscience, Baylor College of Medicine, Houston, TX 77030, United States.
Jeffrey M YauDepartment of Neuroscience, Baylor College of Medicine, Houston, TX 77030, United States. Electronic address: Jeffrey.yau@bcm.edu.

Funding

Determining a Central Locus for Temperature Modulation of Touch SensitivityF31NS135914 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI Juan Carlos Ramirez · 2024 to 2026
$158k
NINDS NIH HHS F31 NS135914
6 · The paper itself

Abstract

backgroundExisting methods to study the effects of skin temperature on mechanical touch perception range from large hot plates, water baths, or bulky, water-controlled thermal contactors which have limited range and resolution. The limited capabilities of these methods prevent the study of thermo-tactile interactions at the finger level in a flexible and precisely controlled manner. NEW

methodHere, we combine small Proportional-Integral-Derivative (PID)-controlled Peltier elements with a calibrated shaker motor for a novel thermo-tactile stimulus delivery system capable of precisely controlling temperature and vibrotactile stimulation to the fingertip. This novel system enables parallel control of mechanical stimulation and thermal stimulation at congruent skin sites of the fingertip. Alternative thermoelectric elements and mechanical actuators could be used in our systems modular configuration.

resultsOur thermo-tactile delivery system can simultaneously deliver precise and stable vibrotactile and thermal stimuli over 30-250 Hz and 20-40°C, respectively, at the fingertip. We validated our system in psychophysical tests and reproduced the established finding that vibration detection thresholds vary according to temperature. COMPARISON WITH EXISTING METHOD(S): Unlike our system, existing methods to study thermo-tactile interactions are restricted to testing skin regions larger than the fingertip or they use tactile probes on the fingertips that are not thermally controlled.

conclusionsOur system represents a novel strategy for combining thermoelectric modules with mechanical actuation to study thermo-tactile interactions at mechanoreceptor-rich fingertips.

Indexed as

Physical StimulationSkin TemperatureThermosensingTouchTouch PerceptionAdultEquipment DesignFemaleFingersHumansMalePsychophysicsSensory ThresholdsTemperatureVibrationYoung AdultDetection thresholdsPsychophysicsSensory cross-modulationSomatosensationThermo-tactileVibrotactile

Identifiers

PMID40754054
PMCPMC12665374

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.