Evidence map›Paper›PMID 40753942›Full record

ArticleBrazilian journal of otorhinolaryngology

Adenoid hypertrophy is directly associated with the severity of OSA in obese children: A pilot study.

Victor Hugo da Costa Ferreira, Carolina Sponchiado Miura, Bruna de Alencar Custodio Lupoli, Denny Marcos Garcia, Bruno Carvalho Portes Lopes, Fernando Gustavo Stelzer, Fábio Lourenço Romano, Tabata Luna Garavazzo Tavares, Alan Luiz Eckeli, Fabiana Cardoso Pereira Valera

Abstract read
In one paragraph

Article in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Progression of mild sleep-disordered breathing in children managed with watchful waiting.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Trial
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Victor Hugo da Costa FerreiraUniversidade de São Paulo (USP), Faculdade de Medicina de Ribeirão Preto (FMRP), Ribeirão Preto, SP, Brazil.
Carolina Sponchiado MiuraUniversidade de São Paulo (USP), Faculdade de Medicina de Ribeirão Preto (FMRP), Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Ribeirão Preto, SP, Brazil.
Bruna de Alencar Custodio LupoliUniversidade de São Paulo (USP), Faculdade de Medicina de Ribeirão Preto (FMRP), Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Ribeirão Preto, SP, Brazil.
Denny Marcos GarciaUniversidade de São Paulo (USP), Faculdade de Medicina de Ribeirão Preto (FMRP), Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Ribeirão Preto, SP, Brazil.
Bruno Carvalho Portes LopesUniversidade de São Paulo (USP), Faculdade de Medicina de Ribeirão Preto (FMRP), Departamento de Ortopedia e Anestesiologia, Ribeirão Preto, SP, Brazil.
Fernando Gustavo StelzerUniversidade de São Paulo (USP), Faculdade de Medicina de Ribeirão Preto (FMRP), Departamento de Neurologia e Ciências Comportamentais, Ribeirão Preto, SP, Brazil.
Fábio Lourenço RomanoUniversidade de São Paulo (USP), Faculdade de Odontologia de Ribeirão Preto (FORP), Departamento de Clínicas Pediátricas, Ortodontia, Ribeirão Preto, SP, Brazil.
Tabata Luna Garavazzo TavaresUniversidade de São Paulo (USP), Faculdade de Medicina de Ribeirão Preto (FMRP), Departamento de Neurologia e Ciências Comportamentais, Ribeirão Preto, SP, Brazil.
Alan Luiz EckeliUniversidade de São Paulo (USP), Faculdade de Medicina de Ribeirão Preto (FMRP), Departamento de Neurologia e Ciências Comportamentais, Ribeirão Preto, SP, Brazil.
Fabiana Cardoso Pereira ValeraUniversidade de São Paulo (USP), Faculdade de Medicina de Ribeirão Preto (FMRP), Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Ribeirão Preto, SP, Brazil. Electronic address: facpvalera@fmrp.usp.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to evaluate which physical findings, observed during both awake and DISE examinations, correlate best with polysomnographic severity in obese children with Obstructive Sleep Apnea (OSA).

methodsChildren diagnosed with pediatric OSA and obesity (BMI > 95th percentile) were evaluated. All underwent polysomnography to confirm the OSA diagnosis. Demographic data, physical exams, and ENT clinical evaluations were also collected. DISE (drug induced sleep endoscopy) was performed just before adenotonsillectomy, following Boudewyns' protocol to assess pharyngeal collapse.

resultsNineteen obese children with OSA were evaluated, with 37% showing adenoid hypertrophy (>75%) on nasal endoscopy, and 53% presented tonsillar hypertrophy on physical examination. The median AHI (apnea / hypopnea index) was 7 (range: 3; 17): 9 had mild, 2 moderate, and 8 severe OSA. Children with adenoid hypertrophy had higher arousal indices, AHI, REM (rapid eye movement) AHI, OAHI (obstructive AHI) and lower minimum saturation compared to those without obstruction, in both awake and DISE evaluations. The presence of other factors, such as tonsillar hypertrophy, tongue base obstruction, palatal and epiglottic collapses, or hypotonia, was not associated with OSA severity or polysomnographic findings in either awake or DISE exams.

conclusionIn our cohort, adenoid hypertrophy was the factor most strongly correlated with OSA severity in obese children. This correlation was consistent between awake physical examination and DISE findings. LEVEL OF EVIDENCE: 3:

Indexed as

AdenoidsPediatric ObesitySleep Apnea, ObstructiveBody Mass IndexChildChild, PreschoolFemaleHumansHypertrophyMalePilot ProjectsPolysomnographySeverity of Illness IndexChildrenDrug-induced sleep endoscopyObesityObstructive sleep apnea

Identifiers

PMID40753942
PMCPMC12624784

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.