Evidence map›Paper›PMID 40753675›Full record

ArticleApplied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine2025

Automated radiosynthesis of [

Spenser R Simpson, Kamal Jouad, Allison J Clay, Arijit Ghosh, Justin H Wilde, Diane A Dickie, Amy L Vavere, Kiel D Neumann

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Spenser R SimpsonDepartment of Radiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA. Electronic address: spenser.simpson@stjude.org.
Kamal JouadDepartment of Radiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA. Electronic address: kamal.jouad@vumc.org.
Allison J ClayDepartment of Radiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA. Electronic address: allison.clay@stjude.org.
Arijit GhoshDepartment of Radiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA. Electronic address: arijit.ghosh@stjude.org.
Justin H WildeDepartment of Radiology and Medical Imaging, University of Virgina, 480 Ray C. Hunt Drive, Charlottesville, VA, 22903, USA. Electronic address: justin.h.wilde@gmail.com.
Diane A DickieDepartment of Chemistry, University of Virgina, McCormick Road, Charlottesville, VA, 22904, USA. Electronic address: dad8v@virginia.edu.
Amy L VavereDepartment of Radiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA. Electronic address: amy.vavere@stjude.org.
Kiel D NeumannDepartment of Radiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA; Center for Infectious Disease Research, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA. Electronic address: kiel.neumann@stjude.org.

Funding

Novel imaging agents of oxidative stress in the pathophysiology of the central nervous systemR01EB028338 · NIBIB · UNIVERSITY OF VIRGINIA · PI NEUMANN, KIEL · 2020 to 2020
$2.1M
[18F]fluoromannitol: A novel imaging agent to delineate osteomyelitis in sickle cell diseaseR01AI192221 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Amanda Marie Green, Kiel Neumann · 2025 to 2026
$1.8M
NIAID NIH HHS R01 AI192221NIBIB NIH HHS R01 EB028338
6 · The paper itself

Abstract

Bacterial infections remain a significant global health concern, exacerbated by rising antimicrobial resistance and a growing immunocompromised population. Improved diagnostic tools are essential to accurately detect infections, distinguish them from sterile inflammation, and reduce unnecessary antibiotic use that drives resistance. Positron Emission Tomography (PET) has emerged as a powerful non-invasive modality for detecting and monitoring infections in vivo, especially when conventional diagnostics are inconclusive. [

Indexed as

Fluorine RadioisotopesMannoseRadiopharmaceuticalsAutomationPositron-Emission TomographyFluorine-18Fluorine RadioisotopesMannoseRadiopharmaceuticalsAutomationBacteriaFluorine-18Infectious diseasePET imagingPre-clinicalRadiochemistry

Identifiers

PMID40753675
PMCPMC12410079

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.