Evidence map›Paper›PMID 40753399›Full record

ArticleBMC neurology2025

Extreme dipping blood pressure pattern is associated with increased mortality in hemorrhagic stroke patients: a retrospective cohort study.

Feng Nong, Wei Zhu, Yan Jiang

Abstract read
In one paragraph

Article in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Feng NongDepartment of Nursing, West China Hospital Sichuan University , West China School of Nursing, Sichuan University, Chengdu, China.
Wei ZhuDepartment of Nursing, West China Hospital Sichuan University , West China School of Nursing, Sichuan University, Chengdu, China.
Yan JiangDepartment of Nursing, West China Hospital Sichuan University , West China School of Nursing, Sichuan University, Chengdu, China. hxhljy2018@163.com.

Funding

This study was funded by: 1·3·5 project for disciplines of excellence-Clinical Research Incubation Project, West China Hospital, Sichuan University 2022HXFH018
6 · The paper itself

Abstract

backgroundBlood pressure management strategies in patients with hemorrhagic stroke remain ineffective in reducing mortality. The circadian blood pressure pattern has been shown to be associated with mortality in patients with non-hemorrhagic stroke, but few studies have explored this association in patients with hemorrhagic stroke. We aimed to investigate the relationship between circadian blood pressure pattern and mortality in patients with hemorrhagic stroke. METHODS AND

resultsAdult hemorrhagic stroke patients hospitalized in intensive care unit for more than 24 h in the Medical Information Mart for Intensive Care (MIMIC-IV) database were recruited for this retrospective cohort study. All patients were divided into the dipping group, the nondipping group, the reverse dipping group and the extreme dipping group. We used binary logistic regression analysis to explore the relationship between circadian blood pressure patterns and mortality of patients with hemorrhagic stroke. The overall cohort comprised 1040 patients. The patients in the extreme dipping group had higher mortality than other groups (57.1% versus 15.6%,17.0%, and 22.3%, respectively). After adjusting for covariates, the statistical analysis showed that the extreme dipping pattern was significantly associated with the mortality of hemorrhagic stroke patients in intensive care unit (odds ratio: 4.961[95%CI: 1.289-19.086]). Interaction analysis had no statistical significance in all results.

conclusionsThe extreme dipping pattern may be an important risk factor for increased mortality in patients with hemorrhagic stroke.

Indexed as

Blood PressureCircadian RhythmHemorrhagic StrokeAgedCohort StudiesFemaleHumansIntensive Care UnitsMaleMiddle AgedRetrospective StudiesBlood pressureCircadian blood pressure patternsCircadian rhythmHemorrhagic strokeIntensive care unitMortality

Identifiers

PMID40753399
PMCPMC12318415

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.