Evidence map›Paper›PMID 40753233›Full record

Observational studyBMC surgery2025

Evaluating the efficacy of dilute povidone-iodine versus normal saline for preventing surgical site infections following appendectomy: a prospective observational study in Ghanaian tertiary hospital.

Sulemana Abdul-Latif, Joseph Yorke, Samuel Gyasi Brenu, Joseph Kwaku Oppong, Tonnies Abeku Buckman, Francis Somiah-Kwao Aitpillah, Jonathan Laryea, Gifty Kwakye, Michael Ofoe Adinku, Frank Enoch Gyamfi and 15 more

Abstract readComparative StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Sulemana Abdul-LatifDirectorate of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Joseph YorkeDepartment of Surgery, Kwame Nkrumah University of Science and Technology, KNUST, Kumasi, Ghana.
Samuel Gyasi BrenuDirectorate of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Joseph Kwaku OppongDirectorate of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Tonnies Abeku BuckmanDepartment of Medical Laboratory Science, KAAF University College, Buduburam, Ghana. tonniesb@yahoo.com.
Francis Somiah-Kwao AitpillahDepartment of Surgery, Kwame Nkrumah University of Science and Technology, KNUST, Kumasi, Ghana.
Jonathan LaryeaWinthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Arkansas, USA.
Gifty KwakyeDivision of Colorectal Surgery, University of Michigan Health, Indiana, MI, USA.
Michael Ofoe AdinkuDepartment of Surgery, Kwame Nkrumah University of Science and Technology, KNUST, Kumasi, Ghana.
Frank Enoch GyamfiDirectorate of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Kwabena AgbedinuDirectorate of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Francis Akwaw YamoahDirectorate of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Ishmael KyeiDepartment of Surgery, Kwame Nkrumah University of Science and Technology, KNUST, Kumasi, Ghana.
Samuel MensahDepartment of Surgery, Kwame Nkrumah University of Science and Technology, KNUST, Kumasi, Ghana.
Charles Kofi DallyDirectorate of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Anita Eseenam AgbekoDirectorate of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Dominic Akuoku DarkwaDirectorate of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Kingsley BosompemDirectorate of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Dennis Afful YorkeDirectorate of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Akwasi Opoku AgyapongDirectorate of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Nana Akosua Oppong-NkrumahDirectorate of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Martin Kofi AdjeiDepartment of Internal Medicine, Kwame Nkrumah University of Science and Technology, KNUST, Kumasi, Ghana.
Theodora-Ann Fremponma EllisDirectorate of Accident and Emergency, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Wilfred Sam-Awortwi JnrDirectorate of Anaesthesia and Intensive Care Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Yaa Takyi BaffowaDirectorate of Anaesthesia and Intensive Care Unit, Komfo Anokye Teaching Hospital, Kumasi, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundand Aims: Surgical site infection (SSI) remains a common postoperative complication for patients with acute appendicitis. This study aimed to compare the effectiveness of dilute povidone-iodine and normal saline in preventing post-appendectomy surgical site infections.

methodsThe study included 224 consecutive patients who underwent open appendectomy for acute appendicitis between October 2020 and December 2021 at Komfo Anokye Teaching Hospital in Ghana. Patients were randomly assigned to have irrigation with either povidone iodine or normal saline after appendectomy. The surgical wounds were assessed for infection using the Southampton wound grading system at 5 days post-surgery till 30 days.

resultThe mean age of the patients was 30.8 ± 14.4 years. The overall incidence of SSI was 8.04% (10.7% in the N/S group and 5.4% in the PI group). Both groups had a higher percentage of male patients (58% in the N/S group and 58.9% in the PI group). The mean length of hospital stays for patients with and without SSI was 10.11 ± 5.06 days and 4.69 ± 2.07 days respectively. The mean length of stay for the N/S group and PI group patients was 5.25 ± 2.95 days and 5.02 ± 2.81 days respectively. The mean cost for patients with and without SSI was GHC3,813.64(US$238.3) and GHC2,364.45 (US$147.7) respectively.

conclusionWe conclude that there was no difference in SSI rates when comparing normal saline and povidone-iodine as irrigant fluids in patients undergoing an open appendectomy.

Indexed as

Anti-Infective Agents, LocalAppendectomyAppendicitisPovidone-IodineSaline SolutionSurgical Wound InfectionAdolescentAdultFemaleGhanaHumansLength of StayMaleMiddle AgedProspective StudiesRandom AllocationAnti-Infective Agents, LocalPovidone-IodineSaline SolutionNormal salineOpen appendectomyPovidone iodineSurgical site infections

Identifiers

PMID40753233
PMCPMC12317621

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.