Evidence map›Paper›PMID 40753224›Full record

ArticleVirology journal2025

Spatiotemporal evolution of HCV burden among women of reproductive age: a multinational age-period-cohort analysis.

Zhang Ying, Yan Jing, Weifang Tong, Yue Chaoyan

Abstract read
In one paragraph

Article in Virology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhang Ying *Department of Laboratory Medicine, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Yan Jing *Department of Laboratory Medicine, Jinshan Hospital of Fudan University, Shanghai, China.
Weifang TongSchool of Medicine, Tongji Hospital, Tongji University, Shanghai, China. weifangtong123@163.com.
Yue ChaoyanDepartment of Laboratory Medicine, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China. 20111250007@fudan.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the epidemiology and trends of HCV infection among women aged 15-49, this research aims to inform public health strategies and reduce its global impact by addressing maternal and child transmission risks.

designThis research analyzed GBD data (1990-2021) on HCV in women aged 15-49, examining ASIR, ASPR, ASMR, and ASDR trends by region and age. APC and Bayesian models predicted future trajectories to guide public health policies.

resultsFrom 1990 to 2021, the global burden of hepatitis C virus (HCV) among women aged 15 - 49 witnessed a downward trend. The incidence rate (5.46 per 100,000) and mortality rate (0.068 per 100,000) of acute HCV were notably lower than those of chronic HCV, which stood at an incidence rate of 29.92 per 100,000 and a mortality rate of 1.42 per 100,000. In 2021, regions with a low Sociodemographic Index (SDI) endured the heaviest burden. Oceania, Central Asia, Eastern Europe, and several other regions experienced an upward trend in acute HCV cases; meanwhile, the number of chronic HCV cases increased in most regions, with the exception of Australasia. Pakistan had the highest HCV burden globally. Projections indicate that over the next decade, both the incidence and mortality rates of HCV will continue to decline, yet the total number of cases is expected to rise.

conclusionThis study reveals the complex epidemiological landscape of acute and chronic hepatitis C in women of reproductive age globally. Despite the anticipated decline in standardized incidence and mortality rates of acute and chronic hepatitis C among women of reproductive age worldwide in the coming decade, the actual number of cases continues to increase annually. This underscores the substantial challenges faced by the World Health Organization's goal of eliminating HCV infection by 2030.

Indexed as

Hepatitis CHepatitis C, ChronicAdolescentAdultBayes TheoremCohort StudiesFemaleGlobal HealthHepacivirusHumansIncidenceMiddle AgedSpatio-Temporal AnalysisYoung AdultAge-Period-Cohort AnalysisBayesian ProjectionsGBDHepatitis CWomen of Childbearing Age

Identifiers

PMID40753224
PMCPMC12317561

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.