Evidence map›Paper›PMID 40753223›Full record

Observational studyBMC cardiovascular disorders2025

The impact of atrial fibrillation type on clinical outcomes and antithrombotic therapy at discharge in patients with acute coronary syndrome or undergoing percutaneous coronary intervention: a real-world study.

Yimeng Wang, Jingyang Wang, Yuyuan Shu, Yijing Xin, Yanmin Yang

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yimeng WangEmergency and Intensive Care Center, National Center for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishilu, Xicheng District, Beijing, 100037, China.
Jingyang WangEmergency and Intensive Care Center, National Center for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishilu, Xicheng District, Beijing, 100037, China.
Yuyuan ShuEmergency and Intensive Care Center, National Center for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishilu, Xicheng District, Beijing, 100037, China.
Yijing XinEmergency and Intensive Care Center, National Center for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishilu, Xicheng District, Beijing, 100037, China.
Yanmin YangEmergency and Intensive Care Center, National Center for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishilu, Xicheng District, Beijing, 100037, China. yyminfuwai@163.com.

Funding

High-Level Hospital Clinical Research Funding 2022-GSP-GG-26National Clinical Medical Research Center for Cardiovascular Diseases NCRC2020015
6 · The paper itself

Abstract

backgroundThe type of atrial fibrillation (AF) is assumed as a vital factor in AF patients' prognosis. However, its impact on clinical outcomes remains unclear in patients with AF complicated with acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI).

methodsThis study was a prospective, observational, single center study of adults with AF and ACS/PCI. The primary endpoint was major adverse cardiovascular events (MACE), and secondary endpoint was net adverse clinical outcome events (NACE), a composite of MACE events and major bleeding events.

resultsA total of 1,762 participants were enrolled in this study, 1,137 of them were paroxysmal AF and 625 were non- paroxysmal AF, with a median follow up time of 1,023 days. The mean age of this population was 67 ± 10 and 27.2% were female. Kaplan-Meier curves showed patients were under a higher incidence of both MACE (p < 0.001) and NACE (p < 0.001) in patients with non-paroxysmal AF. Multivariate Cox analysis showed that patients with non-paroxysmal AF had a higher risk of MACE (HR: 1.322; 95%CI 1.074-1.626) and NACE (HR: 1.341; 95%CI 1.095-1.644) compared to those with paroxysmal AF.

conclusionsOur study demonstrated that among patients with ACS/PCI, those with non-paroxysmal AF were more likely to experience MACE and NACE.

Indexed as

Acute Coronary SyndromeAnticoagulantsAtrial FibrillationFibrinolytic AgentsPatient DischargePercutaneous Coronary InterventionAgedFemaleHemorrhageHumansMaleMiddle AgedProspective StudiesRisk AssessmentRisk FactorsTime FactorsAnticoagulantsFibrinolytic AgentsAcute coronary syndromeAtrial fibrillation typeCardiovascular adverse eventsPercutaneous coronary intervention

Identifiers

PMID40753223
PMCPMC12317567

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.