Evidence map›Paper›PMID 40753215›Full record

ReviewParasites & vectors2025

The chemosensory world of mosquitoes: olfactory receptors and their role in blocking mosquito-borne disease transmission.

Sitian Xiong, Jingjing Liang, Shuyang Gao, Zhilong Liu, Hong Zheng, Xuesen Yang, Ying Wang, Shasha Yu

Abstract readReview
In one paragraph

Review in Parasites & vectors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. GravidInsects · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sitian Xiong *Department of Tropical Medicine, College of Military Preventive Medicine, Army Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.
Jingjing Liang *Department of Tropical Medicine, College of Military Preventive Medicine, Army Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.
Shuyang GaoDepartment of Tropical Medicine, College of Military Preventive Medicine, Army Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.
Zhilong LiuDepartment of Tropical Medicine, College of Military Preventive Medicine, Army Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.
Hong ZhengDepartment of Thoracic Surgery, Xinqiao Hospital, Army Medical University, Chongqing, 400037, China.
Xuesen YangDepartment of Tropical Medicine, College of Military Preventive Medicine, Army Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.
Ying WangDepartment of Tropical Medicine, College of Military Preventive Medicine, Army Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, China. wangyingtmmu2016@126.com.
Shasha YuDepartment of Tropical Medicine, College of Military Preventive Medicine, Army Medical University, No. 30 Gaotanyan Street, Shapingba District, Chongqing, 400038, China. shasha102@126.com.

Funding

National Natural Science Foundation of China 82472319
6 · The paper itself

Abstract

Mosquitoes are vectors for a variety of infectious diseases, which pose a significant threat to human health, public well-being, and national security. The increasing prevalence of insecticide resistance has further complicated efforts to control these diseases, highlighting the urgent need for innovative strategies to block their transmission. The mosquito olfactory system, which mediates a wide range of behaviors throughout the mosquito's life cycle, including host-seeking, foraging, oviposition, mating, avoidance behavior, and social communication, offers a promising avenue for intervention. Specifically, olfactory receptors play a crucial role in enabling female mosquitoes to locate human hosts through odor recognition, a process that facilitates the transmission of pathogens responsible for diseases such as malaria and dengue fever. Understanding the roles of these receptors in different mosquito behaviors, their mechanisms of odor recognition, and their involvement in disease transmission could provide valuable insights for developing new mosquito control strategies that target olfactory receptors to effectively block disease spread. This review aims to provide a comprehensive summary of the mosquito olfactory system, including its composition, the mechanisms of action of olfactory receptors, their interactions with repellents, and their potential role in the prevention and control of mosquito-borne diseases.

Indexed as

CulicidaeMosquito VectorsReceptors, OdorantVector Borne DiseasesAnimalsFemaleHumansInsect RepellentsMosquito-Borne DiseasesMosquito ControlInsect RepellentsReceptors, OdorantMosquito-borne diseasesOlfactory receptorsRepellentsVector control

Identifiers

PMID40753215
PMCPMC12318404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.