ReviewTrends in ecology & evolution2025
Long runs of homozygosity are reliable genomic markers of inbreeding depression.
Review in Trends in ecology & evolution, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Runs of Homozygosity Predict Inbreeding Depression Across Taxa: A Systematic Review and Meta-Analysis.Molecular ecology · 2026Pooled it
- Genomic erosion in the assessment of species' extinction risk and recovery potential.The Journal of heredity · 2026Article
- Massive Genetic Diversity Loss Within Asian Elephant Subspecies: New Insights for Determining Conservation Priorities.Genome biology and evolution · 2026Article
- Over-Representation of Sperm-Associated Deleterious Mutations Across Wild and Ex Situ Cheetah (Acinonyx jubatus) Populations.Molecular ecology · 2026Article
- Dissecting cancer in a non-mammalian model: genomic insights from lemon frost geckos.BMC biology · 2026Article
- Imputation in the Wild: Genome-Wide Robustness and Fine-Scale Limitations of Low-Coverage Genomes in Endangered Species.Molecular ecology resources · 2026Article
- Comparing the genomic inbreeding of an isolated rhesus macaque study population to wild populations.bioRxiv : the preprint server for biology · 2026Article
- The Vertebrate Genomes Project Phase I: A global reference genome resource.bioRxiv : the preprint server for biology · 2026Article
- Long-term isolation and introgression shape the genomic distinctiveness of Rice's Whale.bioRxiv : the preprint server for biology · 2026Article
- Long-term small effective population size, inbreeding, and a recessive lethal haplotype drive premature death in the endangered Devils Hole pupfish (bioRxiv : the preprint server for biology · 2026Article
- Reduced Genetic Load and Inbreeding in Reintroduced African Wild Dogs Reflect the Benefits of Admixture.Molecular ecology · 2026Article
- Genomic diversity and the domestication history of cotton (Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Comprehensive analysis of population structure and genomic diversity in fifteen Anatolian sheep breeds.BMC veterinary research · 2026Article
- Genome-Wide Homozygosity Predicts Inbreeding Depression in the Hihi/Stitchbird (Evolutionary applications · 2026Article
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- Article
- Genomic erosion across avian lineages in the context of their evolutionary history.Molecular biology and evolution · 2026Article
- Predicting extinction risk of gibbons from genomes of extinct Yunnan lar gibbon.Genome biology · 2026Article
- Genetic recovery in an alpine climate-sensitive pika species during upward treeline shift.BMC genomics · 2026Article
- No Pedigree, No Problem: Genomic Inbreeding Tracks Genetic Rescue With High Resolution.Evolutionary applications · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
A long-standing goal in ecological, evolutionary, and conservation genetics is to identify genomic correlates of fitness and inbreeding depression. Over the past several years, a growing body of theoretical and empirical work in diverse mammal and bird taxa has established a strong link between long runs of homozygosity (ROH) and inbreeding depression. Here, we develop a new statistic, ID
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.