Evidence map›Paper›PMID 40752834›Full record

ArticleJournal of substance use and addiction treatment2025

Tailored strategies to reduce opioid overdose deaths for pregnant and postpartum women: Examples and lessons learned from the HEALing Communities Study.

Miriam T H Harris, Megan Hall, Sylvia Ellison, JaNae Holloway, Carly Bridden, Sarah M Bagley, Mackenzie Bullard, Deborah Chassler, Avik Chatterjee, Anindita Dasgupta and 8 more

Abstract read
In one paragraph

Article in Journal of substance use and addiction treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Miriam T H HarrisGrayken Center for Addiction, Boston Medical Center, One Boston Medical Center Place, Boston, MA 02118, United States; Section of General Internal Medicine, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, 801 Massachusetts Ave, Boston, MA 02118, United States; Boston Medical Center, Section of General Internal Medicine, 801 Massachusetts Ave, Boston, MA 02118, United States. Electronic address: Miriam.harris@bmc.org.
Megan HallRTI International, 3040 East Cornwallis Road, Research Triangle Park, NC 27709, United States.
Sylvia EllisonOhio State University Wexner Medical Center, HEALing Communities Research, Columbus, OH, United States.
JaNae HollowayRTI International, 3040 East Cornwallis Road, Research Triangle Park, NC 27709, United States.
Carly BriddenBoston Medical Center, Section of General Internal Medicine, 801 Massachusetts Ave, Boston, MA 02118, United States.
Sarah M BagleyGrayken Center for Addiction, Boston Medical Center, One Boston Medical Center Place, Boston, MA 02118, United States; Section of General Internal Medicine, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, 801 Massachusetts Ave, Boston, MA 02118, United States.
Mackenzie BullardBoston Medical Center, Section of General Internal Medicine, 801 Massachusetts Ave, Boston, MA 02118, United States.
Deborah ChasslerBoston University School of Social Work, 264-270 Bay State Road, Boston, MA 02215, United States.
Avik ChatterjeeGrayken Center for Addiction, Boston Medical Center, One Boston Medical Center Place, Boston, MA 02118, United States; Section of General Internal Medicine, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, 801 Massachusetts Ave, Boston, MA 02118, United States; Boston Medical Center, Section of General Internal Medicine, 801 Massachusetts Ave, Boston, MA 02118, United States.
Anindita DasguptaColumbia University Mailman School of Public Health, Sociomedical Sciences, 722 West 168th Street, New York, NY 10032, United States.
Mari-Lynn DrainoniSection of Infectious Diseases, Department of Medicine, Boston Medical Center & Boston University Chobanian & Avedisian School of Medicine, 801 Massachusetts Ave, Boston, MA 02118, United States; Department of Health Law, Policy & Management, Boston University School of Public Health, 801 Massachusetts Ave, Boston, MA 02118, United States; Evans Center for Implementation and Improvement Sciences, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, 801 Massachusetts Ave, Boston, MA 02118, United States.
Dawn E GrussColumbia University, School of Social Work, Social Intervention Group, 1255 Amsterdam Avenue, Suite 807, New York, NY 10027, United States.
Elizabeth JadovichBoston Medical Center, Section of General Internal Medicine, 801 Massachusetts Ave, Boston, MA 02118, United States.
Rachel KatzClinical and Support Options, 8 Atwood Dr, Northampton, MA 01060, United States.
Christine MayotteBoston Medical Center, Section of General Internal Medicine, 801 Massachusetts Ave, Boston, MA 02118, United States.
Jessica L NeufeldColumbia University, School of Social Work, Social Intervention Group, 1255 Amsterdam Avenue, Suite 807, New York, NY 10027, United States.
Emmanuel OgaRTI International, 3040 East Cornwallis Road, Research Triangle Park, NC 27709, United States.
LaShawn GlasgowRTI International, 3040 East Cornwallis Road, Research Triangle Park, NC 27709, United States.

Funding

MassHEAL - Reducing overdose deaths by 40% (2019-2023)UM1DA049412 · NIDA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2019 to 2023
$82.9M
Kentucky CAN HEAL (Communities and Networks Helping End Addiction Long-term)UM1DA049406 · NIDA · UNIVERSITY OF KENTUCKY · PI WALSH, SHARON L. · 2019 to 2022
$81.7M
CHASE: An Innovative County-Level Public Health Response to the Opioid Epidemic in New York StateUM1DA049415 · NIDA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI EL-BASSEL, NABILA, GILBERT, LOUISA · 2019 to 2023
$77.3M
Optimizing HEALing in Ohio Communities (OHiO)-Health Equity SupplementUM1DA049417 · NIDA · OHIO STATE UNIVERSITY · PI FREISTHLER, BRIDGET J, WINHUSEN, T JOHN · 2019 to 2023
$66.3M
HEALing Communities Study Health Equity ResearchUM1DA049394 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI GLASGOW, LASHAWN, KNOTT, CHARLES · 2019 to 2023
$40.6M
NIDA NIH HHS UM1 DA049394NIDA NIH HHS UM1 DA049406NIDA NIH HHS UM1 DA049412NIDA NIH HHS UM1 DA049415NIDA NIH HHS UM1 DA049417
6 · The paper itself

Abstract

introductionPregnant and postpartum women (PPW) face substantial barriers to opioid use disorder (OUD) care despite overdose being a leading cause of maternal mortality in the United States. In this study, we leveraged data from the Helping End Addictions Long Term (HEALing) Communities Study (HCS), a community-engaged implementation trial aimed at reducing opioid overdose deaths, to 1) describe evidence-based practice (EBP) strategies designed to reach PPW and 2) review implementation determinants.

methodsWe analyzed data from 50 communities across Massachusetts, New York, and Ohio that implemented the Communities That HEAL intervention from January 2020 through December 2023. HCS community coalitions used the HCS Opioid-overdose Reduction Continuum of Care Approach (ORCCA) menu to inform the selection of overdose education naloxone distribution (OEND) and medication for OUD (MOUD) EBP strategies. We used the ORCCA tracker, an HCS tool documenting strategy selection and implementation details, to identify and summarize strategies designed for PPW. We reviewed written community action and implementation plans to analyze and summarize implementation determinants.

resultsThe 50 communities included in this analysis selected 29 EBP strategies designed to reach PPW, and 21 (72.4 %) of the selected strategies were implemented, accounting for 3.5 % of all implemented strategies. Most (85.7 %) focused on MOUD, 31.0 % were based in rural communities, and 66.7 %, 23.8 %, and 9.5 % were delivered in healthcare sectors, behavioral health sectors, and criminal legal sectors, respectively. Barriers to implementing OUD strategies intended for PPW included a lack of staff or services with adequate experience, and stigma preventing delivery and engagement. Facilitators included leveraging existing services and community expertise to expand OUD care.

conclusionOur findings indicate a need for greater awareness of OUD among PPW and research on implementation approaches for EBPs that effectively reach this group. Leveraging existing community programs that serve PPW with substance use disorders could help expand tailored services.

Indexed as

Opiate OverdoseOpioid-Related DisordersPregnancy ComplicationsAdultEvidence-Based PracticeFemaleHumansMassachusettsNaloxoneNarcotic AntagonistsPostpartum PeriodPregnancyUnited StatesNaloxoneNarcotic AntagonistsOpioid use disorderOverdosePeripartumPregnancyWomen

Identifiers

PMID40752834
PMCPMC13446575

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.