Evidence map›Paper›PMID 40752676›Full record

ArticleResuscitation2025

Barriers to bystander interventions in suspected opioid-associated out-of-hospital cardiac arrests: A multiple methods study of 9-1-1 calls.

Anjni Joiner, Memu-Iye Kamara, Stephen Powell, Lauren Hart, Gregory Sawin, Melody Glenn, Lee Van Vleet, Michael Supples, Brian Chan, Monique Starks and 1 more

Abstract read
In one paragraph

Article in Resuscitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anjni JoinerDepartment of Emergency Medicine, Duke University School of Medicine, 2301 Erwin Rd Box 3096, Durham, NC 27710, USA; Durham County Emergency Medical Services, 201 E Main St, Ste 660, Durham, NC 27701, USA. Electronic address: anjni.joiner@duke.edu.
Memu-Iye KamaraDepartment of Emergency Medicine, East Carolina University School of Medicine, 600 Moye Blvd, Greenville, NC 27834, USA; Pitt County Emergency Management, 1717 W 5th St, Greenville, NC 27834, USA. Electronic address: kamaram24@ecu.edu.
Stephen PowellDepartment of Emergency Medicine, Wake Forest University School of Medicine, Wake Forest Medical Center, Meads Hall, 2nd Floor, Medical Center Boulevard, Winston-Salem, NC 27157, USA. Electronic address: stpowell@wakehealth.edu.
Lauren HartDepartment of Family Medicine and Community Health, Duke University School of Medicine, DUMC 2914 Durham, NC 27710, USA. Electronic address: lauren.j.hart@duke.edu.
Gregory SawinDepartment of Family Medicine and Community Health, Duke University School of Medicine, DUMC 2914 Durham, NC 27710, USA. Electronic address: gregory.sawin@duke.edu.
Melody GlennDepartment of Emergency Medicine, The University of Arizona at Tucson, Tucson, AZ 85724, USA; Department of Psychiatry, The University of Arizona at Tucson, Behavioral Health Pavilion, 2800 E Ajo Way, Tucson, AZ 85714, USA. Electronic address: melodyglenn@aemrc.arizona.edu.
Lee Van VleetDurham County Emergency Medical Services, 201 E Main St, Ste 660, Durham, NC 27701, USA. Electronic address: lvanvleet@dconc.gov.
Michael SupplesDepartment of Emergency Medicine, Wake Forest University School of Medicine, Wake Forest Medical Center, Meads Hall, 2nd Floor, Medical Center Boulevard, Winston-Salem, NC 27157, USA. Electronic address: mwsupple@wakehealth.edu.
Brian ChanDepartment of Medicine, Section of Addiction Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA. Electronic address: chanbri@oshu.edu.
Monique StarksDivision of Cardiology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA; Duke Clinical Research Institute, Duke University School of Medicine, 300 W Morgan St, Durham, NC 27701, USA. Electronic address: monique.starks@duke.edu.
Audrey L BlewerDepartment of Family Medicine and Community Health, Duke University School of Medicine, DUMC 2914 Durham, NC 27710, USA; Department of Population Health Sciences, Duke University School of Medicine, 215 Morris St, Durham, NC 27701, USA; Duke University School of Nursing, 307 Trent Dr, Durham, NC 27710, USA. Electronic address: audrey.blewer@duke.edu.

Funding

Building Interdisciplinary Research Careers in Women's Health (K12) - Administrative SupplementK12AR084231 · NIAMS · DUKE UNIVERSITY · PI Cindy Amundsen · 2023 to 2026
$2.5M
Evaluation of the Requirements and Critical Features of a Drone-Deployed AED Network to Improve Community-Level Survival after OHCAK23HL153889 · NHLBI · DUKE UNIVERSITY · PI STARKS, MONIQUE ANDERSON · 2020 to 2024
$833k
AHRQ HHS R01 HS029017AHRQ HHS R21 HS029234NHLBI NIH HHS K23 HL153889NIAMS NIH HHS K12 AR084231
6 · The paper itself

Abstract

introductionOpioid-associated out-of-hospital cardiac arrests (OA-OHCA) is a significant problem in the United States. Layperson interventions, including bystander CPR and naloxone may improve survival, but barriers may differ compared to other OHCA. This study aims to describe characteristics of 9-1-1 callers and patients in suspected OA-OHCAs and identify barriers to B-CPR and naloxone administration.

methodsThis was a retrospective multiple methods study of transcribed 9-1-1 calls for suspected OHCA from two counties in North Carolina (5/2022-12/2023). Adult, non-traumatic OHCAs were included. Data were analyzed using descriptive statistics and Student's t-test/Chi

resultsPatients with suspected OA-OHCA were younger than non-suspected OA-OHCA patients (39 vs 58 years [p < 0.01]). Most patients were in a residence, however, this percentage was smaller in suspected OA-OHCA compared with non-suspected OA-OHCA (68 % vs 88 % [p < 0.01]). Most callers in the suspected OA-OHCA group were a friend of the patient (35 %), whereas most callers in the non-suspected OA-OHCA population were a family member (34 %) [p < 0.01]. Qualitative barriers unique to suspected OA-OHCA included: conflicting responsibilities, fear of drugs, and fear of the patient. Naloxone-specific barriers included lack of availability and lack of knowledge of use.

conclusionWe found significant differences in demographics between suspected OA-OHCA compared with non-suspected OA-OHCA. We also identified unique barriers in this population as well as previously described barriers which may be amplified in the setting of suspected drug use. A different approach towards cardiac resuscitation may be needed to maximize treatment and survival.

Indexed as

Analgesics, OpioidCardiopulmonary ResuscitationEmergency Medical ServicesNaloxoneOut-of-Hospital Cardiac ArrestAdultAgedFemaleHumansMaleMiddle AgedNarcotic AntagonistsNorth CarolinaRetrospective StudiesAnalgesics, OpioidNaloxoneNarcotic AntagonistsBystander CPROHCAOpioidsOpioid use disorderOut-of-hospital cardiac arrest

Identifiers

PMID40752676
PMCPMC12376069

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.