Evidence map›Paper›PMID 40752144›Full record

ArticlePsychiatry research2025

Traumatic Brain Injury and Suicidal Thoughts and Behaviors among Post-9/11 Veterans: Investigating Longitudinal Change and Interactions with Mental Health.

Alyssa Bernanke, Nathan A Kimbrel, VA Mid-Atlantic MIRECC Workgroup, Jean C Beckham, Kyle J Bourassa

Abstract read
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Article in Psychiatry research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Alyssa BernankeFeinberg School of Medicine, Northwestern University.
Nathan A KimbrelVA Mid-Atlantic Mental Illness Research, Education and Clinical Center, Durham VA Health Care System; VA Health Services Research and Development Center of Innovation to Accelerate Discovery and Practice Transformation, Durham VA Health Care System; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine.
VA Mid-Atlantic MIRECC WorkgroupVA Mid-Atlantic Mental Illness Research, Education and Clinical Center, Durham VA Health Care System.
Jean C BeckhamVA Mid-Atlantic Mental Illness Research, Education and Clinical Center, Durham VA Health Care System; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine.
Kyle J BourassaVA Mid-Atlantic Mental Illness Research, Education and Clinical Center, Durham VA Health Care System; Department of Psychology, Georgetown University. Electronic address: kyle.bourassa@duke.edu.

Funding

BLRD VA IK6 BX003777BLRD VA IK6 BX006523CSRD VA IK2 CX002694CSRD VA IK6 CX002767
6 · The paper itself

Abstract

Veterans die by suicide at almost twice the rate of non-veterans, and risks for suicide can be further increased after sustaining traumatic brain injury (TBI). This is notable, given that over 20 % of post-9/11 Veterans are estimated to have experienced TBI. Better understanding risk for suicidal thoughts and behaviors (STBs) would allow for improved screening processes and targeted treatment approaches. In this study, we use data from 823 veterans who served after September 11, 2001 and participated in the VISN 6 MIRECC's Post-Deployment Mental Health Study. In total, 511 (62.1 %) veterans reported at least one TBI during their lifetime and 241 (29.3 %) reporting at least one TBI during military deployment. Veterans had more STBs at baseline if they also reported more lifetime TBIs (β = 0.45, CI [0.18, 0.72], p < .001) or deployment TBI (β = 0.53, CI [0.16, 0.90], p = .005). When examining change over 12 years, veterans showed greater increases in STBs if they reported more lifetime TBIs (β = 0.34, CI [0.12, 0.55], p = .002) or deployment TBI (β = 0.62, CI [0.33, 0.91], p < .001). These associations remained when accounting for baseline mental health conditions (depressive symptoms, posttraumatic stress disorder symptoms, and lifetime trauma burden). All reported results accounted for age, gender, self-reported race/ethnic group, and education. Findings suggest that TBI is associated with increases in STBs and emergence of STBs over time. To better differentiate risk, screening measures and treatment for STBs should consider whether brain injury occurred in combat.

Indexed as

Brain Injuries, TraumaticSeptember 11 Terrorist AttacksSuicidal IdeationVeteransAdultFemaleHumansLongitudinal StudiesMaleMiddle AgedStress Disorders, Post-TraumaticEthnic groupGenderSuicidal ideationSuicidal thoughts and behaviorsTraumatic brain injury

Identifiers

PMID40752144
PMCPMC12337214

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.