Evidence map›Paper›PMID 40752014›Full record

ArticleACS infectious diseases2025

Synthetic Multiepitope Protein-Based Plasmonic Immunosensor for Rapid, Label-Free Detection of

Camila Erbereli, Jaqueline Volpe, Nicole Maia, Hélida Monteiro de Andrade, Liline Martins, Semiramis Jamil Hadad do Monte, Rafael Brandão, Adalberto Silva, Lauro Tatsuo Kubota, Dênio Souto

Abstract read
In one paragraph

Article in ACS infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Camila ErbereliLaboratório de Eletroquímica, Eletroanálise e Desenvolvimento de Sensores, Institute of Chemistry, State University of Campinas (UNICAMP), Campinas, SP 13083-970, Brazil.
Jaqueline VolpeLaboratório de Espectrometria, Sensores e Biossensores - Department of Chemistry, Federal University of Paraná (UFPR), Curitiba, PR 81530-900, Brazil.
Nicole MaiaLaboratório de Espectrometria, Sensores e Biossensores - Department of Chemistry, Federal University of Paraná (UFPR), Curitiba, PR 81530-900, Brazil.
Hélida Monteiro de AndradeLaboratório de Leishmanioses, Institute of Biological Sciences, Federal University of Minas Gerais (UFMG), Belo Horizonte, MG 31270-901, Brazil.
Liline MartinsLaboratório de Imunogenética e Biologia Molecular, Federal University of Piaui, Campus Ministro Petrônnio Portella, Teresina, PI 64049-550, Brazil.
Semiramis Jamil Hadad do MonteLaboratório de Imunogenética e Biologia Molecular, Federal University of Piaui, Campus Ministro Petrônnio Portella, Teresina, PI 64049-550, Brazil.
Rafael BrandãoLaboratório de Imunogenética e Biologia Molecular, Federal University of Piaui, Campus Ministro Petrônnio Portella, Teresina, PI 64049-550, Brazil.
Adalberto SilvaLaboratório de Imunogenética e Biologia Molecular, Federal University of Piaui, Campus Ministro Petrônnio Portella, Teresina, PI 64049-550, Brazil.
Lauro Tatsuo KubotaLaboratório de Eletroquímica, Eletroanálise e Desenvolvimento de Sensores, Institute of Chemistry, State University of Campinas (UNICAMP), Campinas, SP 13083-970, Brazil.
Dênio SoutoLaboratório de Espectrometria, Sensores e Biossensores - Department of Chemistry, Federal University of Paraná (UFPR), Curitiba, PR 81530-900, Brazil.ORCID 0000-0003-3276-8797

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptococcosis is a severe fungal infection, particularly in immunosuppressed individuals, causing over 112,000 HIV-related deaths annually. Early and accurate diagnosis is critical, but current methods often lack the necessary sensitivity, specificity, and accessibility for point-of-care use. A major challenge is identifying highly specific bioreceptors for detecting

Indexed as

Antibodies, FungalBiosensing TechniquesCryptococcosisCryptococcusEpitopesSurface Plasmon ResonanceHumansImmunoassayLimit of DetectionAntibodies, FungalEpitopeschimeric proteincryptococcosisfungal infectionimmunosensorsurface plasmon resonance

Identifiers

PMID40752014
PMCPMC12442102

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.