Evidence map›Paper›PMID 40751875›Full record

ReviewProbiotics and antimicrobial proteins2025

Exploring the Therapeutic Landscape of Probiotics in Enteric and Respiratory Viral Infections.

Yashpal Singh Malik, Aakriti Pathania, Ujjwal Kumar De, Manu M, Harsh Panwar, Jaspreet Kaur, Adarsh Mishra, Naveen Kumar, Souvik Ghosh, Varun Kumar Sarkar and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yashpal Singh Malik *College of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana , 141 004, Punjab, India.
Aakriti PathaniaCollege of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana , 141 004, Punjab, India.
Ujjwal Kumar De *Division of Medicine, ICAR-Indian Veterinary Research Institute, Izatnagar, 243 122, Uttar Pradesh, India. ujjwalde@gmail.com.ORCID 0000-0002-7826-0940
Manu MCollege of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana , 141 004, Punjab, India.
Harsh PanwarDepartment of Dairy Microbiology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, 141 004, Punjab, India.
Jaspreet KaurDepartment of Microbiology, Punjab Agricultural University, Ludhiana, 141 004, Punjab, India.
Adarsh MishraCollege of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana , 141 004, Punjab, India.
Naveen KumarICAR-National Institute of High Security Animal Diseases, WOAH Reference Laboratory for Avian Influenza, Anand Nagar, Bhopal462021, Madhya Pradesh, India.
Souvik GhoshOne Health Center for Zoonoses and Tropical Veterinary Medicine, Ross University School of Veterinary Medicine, PO Box 334, Basseterre, West Indies, Saint Kitts and Nevis.
Varun Kumar SarkarDivision of Medicine, ICAR-Indian Veterinary Research Institute, Izatnagar, 243 122, Uttar Pradesh, India.
SakshiDivision of Medicine, ICAR-Indian Veterinary Research Institute, Izatnagar, 243 122, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent times, the understanding of the human microbiome and its impact on health and disease has undergone a paradigm shift, leading to ground-breaking discoveries in the field of probiotics. Probiotics, live microorganisms known for conferring health benefits when administered adequately, have garnered significant interest for their potential to modulate the immune system's response to viral infections in both humans and animals. The emergence of enteric and respiratory viruses as significant global health threats has prompted intensive research efforts to identify novel therapeutic strategies. Traditional antiviral therapies often face challenges such as drug resistance, limited efficacy and adverse effects, underscoring the urgent need for alternative approaches. In this context, probiotics have emerged as a promising avenue for the prevention and treatment of viral infections due to their ability to modulate the host immune response, enhance mucosal barrier function and exert direct antiviral effects. This review aims to provide a comprehensive overview of the therapeutic landscape of probiotics against enteric and respiratory viruses. Based on latest findings from preclinical and clinical studies, we have explored the mechanisms underlying the antiviral activity of probiotics and their potential role in mitigating viral infections. Furthermore, promising avenues for harnessing probiotics as adjunctive or standalone interventions against enteric and respiratory viral infections have been discussed here.

Indexed as

ProbioticsRespiratory Tract InfectionsVirus DiseasesAnimalsAntiviral AgentsGastrointestinal MicrobiomeHumansAntiviral AgentsEnteric infectionImmunomodulationProbioticsRespiratory infectionViral infections

Identifiers

PMID40751875

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.