Evidence map›Paper›PMID 40751524›Full record

ArticleArchives of Iranian medicine2025

Comparative Analysis of Clinical Characteristics in Multi-organ and Single-organ Involvement of IgG4-Related Disease: A Single-center Retrospective Study.

Dong-Ge Han, Chun-Lin Ying, Zi-Ping Cai, Qiao-Yun Tong, Wei Liu

Abstract readComparative Study
In one paragraph

Article in Archives of Iranian medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dong-Ge HanThe First College of Clinical Medical Science, China Three Gorges University, Yichang, China.ORCID 0009-0007-7708-6219
Chun-Lin YingThe First College of Clinical Medical Science, China Three Gorges University, Yichang, China.
Zi-Ping CaiThe First College of Clinical Medical Science, China Three Gorges University, Yichang, China.
Qiao-Yun TongThe First College of Clinical Medical Science, China Three Gorges University, Yichang, China.ORCID 0009-0000-0647-5419
Wei LiuThe First College of Clinical Medical Science, China Three Gorges University, Yichang, China.ORCID 0000-0001-7118-815X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmunoglobulin G4-related disease (IgG4-RD) is a rare, chronic inflammatory condition characterized by fibrosis and tendency for multi-organ involvement. This study aims to analyze the clinical characteristics associated with multi-organ versus single-organ involvement in IgG4-RD, thereby enhancing clinicians' understanding of the differences between these two patient groups and ultimately improving patient prognosis.

methodsWe performed a retrospective analysis of clinical data from 82 patients diagnosed with IgG4-RD admitted to Yichang Central People's Hospital between January 2019 and December 2024.

resultsAmong the 82 patients diagnosed with IgG4-RD, 47 patients (57.32%) exhibited involvement of multiple organs. The incidence of multi-organ involvement was significantly higher in male patients than female patients [63.49% vs. 36.84%, odds ratio (OR): 2.98, 95% confidence intervals (CI): 1.03-8.64,

conclusionThe clinical features associated with multi-organ involvement in IgG4-RD are characterized by significant diversity and complexity. Clinicians must enhance their understanding of the characteristics associated with multi-organ involvement to more effectively improve patient prognosis.

Indexed as

Immunoglobulin G4-Related DiseaseAdultAgedFemaleHumansImmunoglobulin GMaleMiddle AgedPancreasRetrospective StudiesImmunoglobulin GClinical characteristicsImmunoglobulin G4-related diseaseOrgan involvement

Identifiers

PMID40751524
PMCPMC12305410

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