Evidence map›Paper›PMID 40751223›Full record

ArticleAddiction science & clinical practice2025

Pilot testing a novel remotely delivered intensive outpatient program for hospitalized patients with opioid use disorder.

Veronica Szpak, Andrea Velez, Sara Prostko, Naomi Rosenblum, Rie Maurer, Lyndon J Aguiar, Roger D Weiss, Joji Suzuki

Erratum issuedAbstract read
In one paragraph

Article in Addiction science & clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Veronica SzpakDepartment of Psychiatry, Brigham and Women's Hospital, 60 Fenwood Rd, Boston, MA, 02115, USA.
Andrea VelezDepartment of Psychiatry, Brigham and Women's Hospital, 60 Fenwood Rd, Boston, MA, 02115, USA.
Sara ProstkoDepartment of Psychiatry, Brigham and Women's Hospital, 60 Fenwood Rd, Boston, MA, 02115, USA.
Naomi RosenblumDepartment of Psychiatry, Brigham and Women's Hospital, 60 Fenwood Rd, Boston, MA, 02115, USA.
Rie MaurerHarvard Catalyst, Boston,, MA, USA.
Lyndon J AguiarWilliamsville Wellness, 10515 Cabaniss Ln, Hanover, VA, 23069, USA.
Roger D WeissHarvard Medical School, 60 Fenwood Rd, Boston, MA, 02115, USA.
Joji SuzukiDepartment of Psychiatry, Brigham and Women's Hospital, 60 Fenwood Rd, Boston, MA, 02115, USA. jsuzuki2@bwh.harvard.edu.

Funding

Developing and pilot testing a novel remotely delivered intensive outpatient program for individuals with opioid use disorder hospitalized with serious injection-related infectionsR21DA056799 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI SUZUKI, JOJI · 2022 to 2023
$504k
NIDA NIH HHS R21 DA056799NIDA NIH HHS R21DA056799
6 · The paper itself

Abstract

backgroundIndividuals with opioid use disorder (OUD) are frequently hospitalized for injection-related medical complications, yet they often receive inadequate treatment for the OUD itself. We previously conducted a qualitative study to adapt an existing remotely delivered intensive outpatient program (IOP) specifically for hospitalized patients with OUD. We then conducted a pilot feasibility and acceptability study to assess the program.

methodsThe 4-week IOP consisted of asynchronous video content and in-person peer support. The primary outcomes were the feasibility of recruitment, acceptability of the treatment as assessed by the completion of videos, and engagement with the peer recovery coach. Secondary outcomes included OUD treatment retention.

resultsOf the 12 participants, the mean age was 40.9 years, 58.3% were female, and 58.3% had an injection-related serious infection. Results demonstrated potentially acceptable recruitment feasibility (70.6%, 95% CI [48.9-92.3]), but the median percentage of video completion was only 2% (range: 0-16%) and the median percentage of engagement with recovery coach was 31.8% (range: 16.7-66.7%). All participants received medications for OUD (MOUD) during the hospital stay (methadone 83%, buprenorphine 17%), and 33.3% remained retained in MOUD treatment at 28 days.

conclusionsHospitalized patients with OUD desired additional support through an IOP along with MOUD. While recruitment feasibility was acceptable, the overall program was not. Future research should explore IOP content that is more personalized and engaging while also including peer support.

Indexed as

Ambulatory CareOpiate Substitution TreatmentOpioid-Related DisordersAdultBuprenorphineFeasibility StudiesFemaleHospitalizationHumansMaleMethadoneMiddle AgedPatient Acceptance of Health CarePilot ProjectsTelemedicineBuprenorphineMethadone

Identifiers

PMID40751223
PMCPMC12317519

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.