Evidence map›Paper›PMID 40751109›Full record

ArticleInternational journal of computer assisted radiology and surgery2025

BEA-CACE: branch-endpoint-aware double-DQN for coronary artery centerline extraction in CT angiography images.

Yuyang Zhang, Gongning Luo, Wei Wang, Shaodong Cao, Suyu Dong, Daren Yu, Xiaoyun Wang, Kuanquan Wang

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Article in International journal of computer assisted radiology and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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8 authors.

Yuyang ZhangFaculty of Computing, Harbin Institute of Technology, Harbin, 150001, China.
Gongning LuoFaculty of Computing, Harbin Institute of Technology, Harbin, 150001, China.
Wei WangSchool of Computer Science and Technology, Harbin Institute of Technology, Shenzhen, 518055, China.
Shaodong CaoDepartment of Radiology, Fourth Affiliated Hospital of Harbin Medical University, Harbin, 150001, China.
Suyu DongCollege of Computer and Control Engineering, Northeast Forestry University, Harbin, 150040, China.
Daren YuDepartment of Cardiology, Fourth Affiliated Hospital of Harbin Medical University, Harbin, 150001, China.
Xiaoyun WangDepartment of Cardiology, Fourth Affiliated Hospital of Harbin Medical University, Harbin, 150001, China.
Kuanquan WangFaculty of Computing, Harbin Institute of Technology, Harbin, 150001, China. wangkq@hit.edu.cn.

Funding

National Natural Science Foundation of China 62001141National Natural Science Foundation of China 62001144National Natural Science Foundation of China 62272135National Natural Science Foundation of China 62372135Science, Technology and Innovation Commission of Shenzhen Municipality JCYJ20210324131800002Science, Technology and Innovation Commission of Shenzhen Municipality RCBS20210609103820029
6 · The paper itself

Abstract

purposeIn order to automate the centerline extraction of the coronary tree, three challenges must be addressed: tracking branches automatically, passing through plaques successfully, and detecting endpoints accurately. This study aims to develop a method to solve the three challenges.

methodsWe propose a branch-endpoint-aware coronary centerline extraction framework. The framework consists of a deep reinforcement learning-based tracker and a 3D dilated CNN-based detector. The tracker is designed to predict the actions of an agent with the objective of tracking the centerline. The detector identifies bifurcation points and endpoints, assisting the tracker in tracking branches and terminating the tracking process automatically. The detector can also estimate the radius values of the coronary artery.

resultsThe method achieves the state-of-the-art performance in both the centerline extraction and radius estimate. Furthermore, the method necessitates minimal user interaction to extract a coronary tree, a feature that surpasses other interactive methods.

conclusionThe method can track branches automatically, pass through plaques successfully and detect endpoints accurately. Compared with other interactive methods that require multiple seeds, our method only needs one seed to extract the entire coronary tree.

Indexed as

Computed Tomography AngiographyCoronary AngiographyCoronary Artery DiseaseCoronary VesselsRadiographic Image Interpretation, Computer-AssistedAlgorithmsDeep LearningHumansImaging, Three-DimensionalCoronary artery centerline extractionCoronary CT angiographyDeep learningDeep reinforcement learning

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.