ArticleDiabetologia2025
Non-autoimmune diabetes in young people from Assam, India: the PHENOEINDY-2 study.
Article in Diabetologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Subtypes of pre-diabetes in rural adolescent girls from India (DERVAN-11).BMJ open diabetes research & care · 2026Article
- Article
- Comparative performance of multiple novel obesity indices for MAFLD screening in Chinese children: the body roundness index as a practical predictor.Frontiers in medicine · 2026Article
- Type 5 diabetes: a 70-year perspective and its implications for the Americas.Lancet regional health. Americas · 2025Review
- Article
- Continuous Glucose Monitoring Metrics in Asians Without Diabetes: Differentiating Prediabetes From Normoglycemia.Journal of diabetes science and technology · 2025Article
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Authors and funding
14 authors.
Funding
Abstract
aims/hypothesisIn the Western world, non-autoimmune diabetes in the young is believed to be driven by overweight/obesity and insulin resistance. However, it is increasingly being reported in undernourished people in low- and middle-income countries, including India. We hypothesised that these patients would show markers of chronic undernutrition and a 'thin-fat' phenotype and be predominantly beta cell-deficient.
methodsWe studied young patients (clinically diagnosed with type 2 diabetes at <40 years) who attended the outpatient department of Assam Medical College and Hospital, Dibrugarh (in North-East India). We measured weight, height, waist and hip circumference, haemoglobin, fasting glucose, HbA
resultsThe study included 252 control participants (136 male participants, median age 30 years, BMI 23.0 kg/m CONCLUSIONS/
interpretationDiabetes in the young people of this impoverished population is heterogeneous, but the majority of patients are not overweight/obese or insulin-resistant. Overall, these participants conform to the thin-fat phenotype, and their diabetes is predominantly driven by beta cell deficiency. The sociodemographic history and physical characteristics of this population suggest a role for multigenerational undernutrition in the aetiology of non-autoimmune diabetes in these young patients from Assam.
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