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ArticleClinical rheumatology2025

Prevalence and Predictors of Residual Symptoms in Rheumatoid Arthritis Patients in SDAI Remission: A Cross-Sectional Study Using the Illustrated Okomarigoto Sheet.

Kensuke Koyama, Tetsuro Ohba, Ryousuke Koizumi, Hirotaka Haro

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Article in Clinical rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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3 · Its place in the literature

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3 citing papers in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Kensuke KoyamaDepartment of Rheumatology, Nirasaki City Hospital, 3-5-3 Honcho, Nirasaki, Yamanashi, 407-0024, Japan. kkoyama@yamanashi.ac.jp.ORCID http://orcid.org/0000-0001-6680-3445
Tetsuro OhbaDepartment of Orthopedic Surgery, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Ryousuke KoizumiDepartment of Orthopedic Surgery, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.
Hirotaka HaroDepartment of Orthopedic Surgery, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study investigated residual symptoms in patients with rheumatoid arthritis (RA) who had achieved remission based on the Simplified Disease Activity Index (SDAI) using the "Okomarigoto sheet" (OS) assessment tool.

methodsThe OS measures morning stiffness, pain, and fatigue through five questions. Each item was rated from 0 (none) to 2 (severe), yielding a total score between 0 and 30, with higher scores indicating greater symptom severity. OS scores were evaluated in 200 patients in SDAI remission. Patients were classified based on OS scores (0 vs. non-zero), and regression analysis was conducted to identify factors associated with residual symptoms.

resultsResidual symptoms were observed in 61.5% of patients. The most persistent symptoms were morning stiffness (27%), pain (21.5%), and fatigue (23%). Significant predictors of a non-zero OS score included female sex (OR 2.70, 95%CI 1.27-5.73), disease duration (OR 0.96, 95%CI 0.92-0.99), tender joint counts (OR 5.75, 95%CI 1.15-28.9), and Patient Global Assessment (OR 2.91, 95% CI 1.32-6.38).

conclusionsThe OS effectively detected residual symptoms in RA patients who had reached SDAI remission. Incorporating OS into patient-reported outcome measures and shared decision-making may enhance treatment strategies and improve patient satisfaction. KEY POINTS: • Utilizing a novel patient-reported outcome assessment tool incorporating illustrations and onomatopoeia for individuals with rheumatoid arthritis, 61.5% of patients were identified as experiencing residual symptoms despite achieving remission according to the Simplified Disease Activity Index. Risk factors for residual symptoms identified through the Okomarigoto sheet included female sex, the number of tender joints, and the patient global assessment.

Indexed as

Antirheumatic AgentsArthritis, RheumatoidAdultAgedCross-Sectional StudiesFatigueFemaleHumansMaleMiddle AgedPainPrevalenceRemission InductionSeverity of Illness IndexAntirheumatic AgentsAssessment toolIllustrationOkomarigoto sheetPatient global assessmentPatient-reported outcomeRemissionResidual symptomsRheumatoid arthritisSDAITender joint counts

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.