Evidence map›Paper›PMID 40750764›Full record

ArticleNature communications2025

Intestinal CD4

Yasuhiro Nemoto, Ryo Morikawa, Yuki Yonemoto, Shohei Tanaka, Yuria Takei, Shigeru Oshima, Takashi Nagaishi, Kiichiro Tsuchiya, Tetsuya Nakamura, Kento Takenaka and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yasuhiro NemotoDepartment of Gastroenterology and Hepatology, Institute of Science Tokyo, Tokyo, Japan. ynemoto.gast@tmd.ac.jp.
Ryo MorikawaDepartment of Gastroenterology and Hepatology, Institute of Science Tokyo, Tokyo, Japan.
Yuki YonemotoDepartment of Gastroenterology and Hepatology, Institute of Science Tokyo, Tokyo, Japan.
Shohei TanakaDepartment of Gastroenterology and Hepatology, Institute of Science Tokyo, Tokyo, Japan.
Yuria TakeiDepartment of Gastroenterology and Hepatology, Institute of Science Tokyo, Tokyo, Japan.
Shigeru OshimaDepartment of Gastroenterology and Hepatology, Institute of Science Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0003-1186-9177
Takashi NagaishiDepartment of Gastroenterology and Hepatology, Institute of Science Tokyo, Tokyo, Japan.
Kiichiro TsuchiyaDepartment of Gastroenterology and Hepatology, Institute of Science Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0002-1977-8707
Tetsuya NakamuraDepartment of Gastroenterology and Hepatology, Institute of Science Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0002-4244-9119
Kento TakenakaDepartment of Gastroenterology and Hepatology, Institute of Science Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0002-7861-8383
Kazuo OhtsukaDepartment of Gastroenterology and Hepatology, Institute of Science Tokyo, Tokyo, Japan.
Xigui ChenDepartment of Neuropathology, Center for Brain Integration Research, Institute of Science Tokyo, Tokyo, Japan.
Hitoshi OkazawaDepartment of Neuropathology, Center for Brain Integration Research, Institute of Science Tokyo, Tokyo, Japan.
Ryuichi OkamotoDepartment of Gastroenterology and Hepatology, Institute of Science Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0002-7047-571X
Mamoru WatanabeDepartment of Gastroenterology and Hepatology, Institute of Science Tokyo, Tokyo, Japan.
Ulrich H von AndrianDepartment of Immunology, Harvard Medical School, Boston, MA, USA. uva@hms.harvard.edu.ORCID http://orcid.org/0000-0003-4231-2283

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intestinal mucosa harbors diverse lymphocyte populations, including double negative CD4

Indexed as

Antigen-Presenting CellsCD4-Positive T-LymphocytesImmune ToleranceIntestinal MucosaReceptors, Antigen, T-Cell, alpha-betaAnimalsAntigen PresentationCD8 AntigensCell MovementCrohn DiseaseFemaleHistocompatibility Antigens Class IIHLA-DR AntigensHumansIntestine, SmallLymph NodesCD8 AntigensHistocompatibility Antigens Class IIHLA-DR AntigensReceptors, Antigen, T-Cell, alpha-beta

Identifiers

PMID40750764
PMCPMC12316896

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.