Evidence map›Paper›PMID 40750762›Full record

ArticleNature communications2025

Acquisition of Escherichia coli carrying extended-spectrum ß-lactamase and carbapenemase genes by hospitalised children with severe acute malnutrition in Niger.

Kirsty Sands, Aditya Kumar Lankapalli, Giulia Lai, Brekhna Hassan, Edward Ar Portal, Jordan At Mathias, Ian Boostrom, Mei Li, Kate Cook, Shonnette Premchand-Branker and 9 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Microbial genomics · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Kirsty SandsIneos Oxford Institute for Antimicrobial Research, Department of Biology, University of Oxford, Oxford, UK. Kirsty.sands@biology.ox.ac.uk.ORCID http://orcid.org/0000-0001-5049-4481
Aditya Kumar LankapalliIneos Oxford Institute for Antimicrobial Research, Department of Biology, University of Oxford, Oxford, UK.
Giulia LaiDivision of Infection and Immunity, Cardiff University, Cardiff, UK.
Brekhna HassanDivision of Infection and Immunity, Cardiff University, Cardiff, UK.
Edward Ar PortalIneos Oxford Institute for Antimicrobial Research, Department of Biology, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0003-2142-3443
Jordan At MathiasDivision of Infection and Immunity, Cardiff University, Cardiff, UK.
Ian BoostromDivision of Infection and Immunity, Cardiff University, Cardiff, UK.ORCID http://orcid.org/0000-0001-6892-1058
Mei LiIneos Oxford Institute for Antimicrobial Research, Department of Biology, University of Oxford, Oxford, UK.
Kate CookIneos Oxford Institute for Antimicrobial Research, Department of Biology, University of Oxford, Oxford, UK.
Shonnette Premchand-BrankerIneos Oxford Institute for Antimicrobial Research, Department of Biology, University of Oxford, Oxford, UK.
Lim S JonesPublic Health Wales Microbiology, University Hospital of Wales, Cardiff, UK.
Nathan Sayinzonga-MakombeEpicentre, Maradi, Niger.
Sheila IsanakaDepartment of Research, Epicentre, Paris, France.
Rupa KanapathipillaiMédecins Sans Frontières, Paris, France.
Christopher MambulaMédecins Sans Frontières, Paris, France.
Isabelle MouniamanMédecins Sans Frontières, Paris, France.
Céline LangendorfDepartment of Research, Epicentre, Paris, France.
Timothy R WalshIneos Oxford Institute for Antimicrobial Research, Department of Biology, University of Oxford, Oxford, UK.
Owen B SpillerDivision of Infection and Immunity, Cardiff University, Cardiff, UK.ORCID http://orcid.org/0000-0002-9117-6911

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hospitalisation and routine antibiotic treatment are recommended for children with complicated severe acute malnutrition (SAM) but this may exacerbate antimicrobial resistance. Here, we investigate carriage of Gram-negative bacteria in children under five years of age receiving treatment for SAM in Niger, comparing the frequency of colonisation with bacteria carrying resistance genes at admission, during hospital stay and at discharge. E. coli isolates carrying a bla

Indexed as

Bacterial Proteinsbeta-LactamasesEscherichia coliEscherichia coli InfectionsSevere Acute MalnutritionAnti-Bacterial AgentsChild, PreschoolFemaleHospitalizationHumansInfantMaleMicrobial Sensitivity TestsNigerWhole Genome SequencingAnti-Bacterial AgentsBacterial Proteinsbeta-Lactamasescarbapenemase

Identifiers

PMID40750762
PMCPMC12317043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.