Evidence map›Paper›PMID 40750729›Full record

ArticleEJNMMI research2025

Differentiation and correlation of regional uptake heterogeneity with cardiac dysfunction in biopsy-proven transthyretin amyloid cardiomyopathy using quantitative single-photon emission computed tomography/computed tomography: a single-center, cross-sectional study.

Masakazu Tsujimoto, Hideki Kawai, Shingo Tanahashi, Masayoshi Sarai, Yasuki Asada, Hideo Izawa

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Masakazu TsujimotoDepartment of Medical Equipment Engineering, Clinical Collaboration Unit, School of Medical Sciences, Fujita Health University, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan. mckz-t@fujita-hu.ac.jp.ORCID http://orcid.org/0000-0003-2980-5366
Hideki KawaiDepartment of Cardiology, School of Medicine, Fujita Health University, Toyoake, Japan.
Shingo TanahashiDepartment of Radiology, Fujita Health University Hospital, Toyoake, Japan.
Masayoshi SaraiDepartment of Cardiology, School of Medicine, Fujita Health University, Toyoake, Japan.
Yasuki AsadaDepartment of Medical Equipment Engineering, Clinical Collaboration Unit, School of Medical Sciences, Fujita Health University, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan.
Hideo IzawaDepartment of Cardiology, School of Medicine, Fujita Health University, Toyoake, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac amyloidosis requires quantitative assessment using technetium-99m pyrophosphate (

methodsForty patients diagnosed via heart biopsy and genetic analysis (20 ATTR-CM; 4 light-chain amyloidosis, 16 non-amyloidosis) were enrolled. The mean SUVs of the heart and aorta were measured using SPECT images. Discrimination performance was evaluated by comparing each SUV, the heart-to-aorta ratio (rSUV

resultsAll metrics were significantly different between the ATTR-CM and non-amyloidosis groups. The rSUV

conclusionsThis study demonstrated that quantitative SPECT analysis provides a valuable tool for the diagnostic evaluation and differentiation of ATTR-CM. The rSUV

Indexed as

AmyloidosisNon-invasive diagnosisSingle-photon emission computed tomography

Identifiers

PMID40750729
PMCPMC12316665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.