Evidence map›Paper›PMID 40750725›Full record

ArticleClinical pharmacokinetics2025

Author's Reply to Helsby and Hannam: 'Understanding Voriconazole Metabolism: A Middle-Out Physiologically-Based Pharmacokinetic Modelling Framework Integrating In Vitro and Clinical Insights'.

Ayatallah Saleh, Josefine Schulz, Jan-Frederik Schlender, Linda B S Aulin, Amrei-Pauline Konrad, Franziska Kluwe, Gerd Mikus, Wilhelm Huisinga, Charlotte Kloft, Robin Michelet

Abstract readLetter
In one paragraph

Article in Clinical pharmacokinetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ayatallah SalehDepartment of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universitaet Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0002-8161-9854
Josefine SchulzDepartment of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universitaet Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0002-0968-5873
Jan-Frederik SchlenderBiomedical Research, Basel, Switzerland.
Linda B S AulinDepartment of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universitaet Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0003-4840-5704
Amrei-Pauline KonradDepartment of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universitaet Berlin, Berlin, Germany.ORCID http://orcid.org/0009-0001-2692-7061
Franziska KluweDepartment of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universitaet Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0002-5985-9683
Gerd MikusDepartment of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universitaet Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0003-1783-133X
Wilhelm HuisingaInstitute of Mathematics, University of Potsdam, Potsdam, Germany.ORCID http://orcid.org/0000-0002-5249-3914
Charlotte Kloft *Department of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universitaet Berlin, Berlin, Germany. charlotte.kloft@fu-berlin.de.ORCID http://orcid.org/0000-0001-9344-8514
Robin Michelet *Department of Clinical Pharmacy and Biochemistry, Institute of Pharmacy, Freie Universitaet Berlin, Berlin, Germany. robin.michelet@fu-berlin.de.ORCID http://orcid.org/0000-0002-5485-607X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40750725
PMCPMC12414042

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.