ArticleScientific reports2025
Spectrophotometric investigation of cocarboxylase interaction with pyridoxine hydrochloride and their interactional properties.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The interactions of vitamin B6 (pyridoxine hydrochloride) with different concentrations of cationic compounds (cocarboxylase or thiamine pyrophosphate chloride) were investigated in an aqueous solution using UV-VIS absorption spectroscopy. The results depict a hyperchromic shift at 300 ± 1 nm, a hypochromic shift at 330 ± 1 nm with increasing concentration of carboxylase, and an isosbestic point at 312 nm. Hydrophilic-hydrophilic (hydrogen bonding) interaction is the dominating force for the association of two compounds. The binding constant (K
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