ArticleBMJ open2025
Chlamydia and gonorrhoea infections in young Kenyan HIV-negative cisgender men who have sex with men and transgender women: a multicentre cohort study.
Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Prevalence of and Factors Associated With Urethral and Rectal STIs Among a Cross-Sectional Sample Men Who Have Sex With Men.Sexually transmitted diseases · 2026Article
- World Health Organization-Recommended Periodic Presumptive Treatment Versus Doxycycline Post-Exposure Prophylaxis for Sexually Transmitted Infection Control Among Men Who Have Sex With Men in Kenya: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
objectivesTo assess the prevalence, incidence and factors associated with
designProspective cohort.
settingKisumu, Nairobi and coastal Kenya.
participants650 young adult participants (570 MSM and 80 TGW) recruited at three research clinics. Inclusion criteria were HIV-negative status, age 18-29 years, assigned male sex at birth, identification as cisgender male or transgender female and reported anal intercourse with a man in the past 3 months. PRIMARY AND SECONDARY OUTCOME MEASURES: Urine, rectal and oropharyngeal samples were tested for CT/NG infection at two different time points (∼6 months apart), using nucleic acid amplification. We compared CT/NG prevalence and incidence in MSM versus TGW and used Poisson regression to compare risk for each group after adjustment for other correlates of prevalent and incident CT/NG infection.
resultsPrevalence of CT/NG infection at any anatomic site was 15.8% and 27.5% in MSM and TGW, respectively (p=0.009). CT/NG incidence was 27.2 (95% CI 21.3 to 34.7) and 24.5 (95% CI 12.3 to 49.0) per 100 person years for MSM and TGW, respectively (p=0.784). In multivariable analysis, there was no difference in prevalence or incidence by gender identity. Baseline CT/NG infection was more prevalent among TGW (adjusted prevalence ratio 1.61, 95% CI 0.99 to 2.62). Incident CT/NG infection was increased among participants with baseline CT/NG infection (adjusted incidence rate ratio (aIRR) 3.14, 95% CI 1.94 to 5.07) and self-reported pre-exposure prophylaxis use (aIRR 1.75, 95% CI 1.04 to 2.93).
conclusionDespite higher prevalence of CT/NG infections among TGW at baseline, there were no differences in CT/NG prevalence and incidence between TGW and MSM, after adjustment for potential confounders. Improved condom use, effective partner notification and treatment, and new strategies such as doxycycline post-exposure prophylaxis are needed to reduce CT/NG infections in both MSM and TGW in settings where regular testing is not possible.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.