Evidence map›Paper›PMID 40750278›Full record

ArticleBMJ open2025

My Back Exercise app: an automated exercise intervention supported by educational notifications, a sleep programme and diet advice to improve function in people with chronic non-specific low back pain - protocol for a superiority, adaptive multi-arm multi-stage randomised controlled trial.

Anelise Moreti Cabral Silveira, Josielli Comachio, Carlos Mesa-Castrillon, Katharine Roberts, Paula Beckenkamp, Emma K Ho, Manuela L Ferreira, Christopher J Gordon, Serigne N Lo, Kim L Bennell and 3 more

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anelise Moreti Cabral SilveiraFaculty of Medicine and Health, Sydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales, Australia amor0266@uni.sydney.edu.au.ORCID http://orcid.org/0000-0003-2179-3620
Josielli ComachioFaculty of Medicine and Health, Sydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-3286-6998
Carlos Mesa-CastrillonFaculty of Medicine and Health, Sydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales, Australia.
Katharine RobertsFaculty of Medicine and Health, Sydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales, Australia.
Paula BeckenkampFaculty of Medicine and Health, Sydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0003-3986-6111
Emma K HoFaculty of Medicine and Health, Sydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-2479-0081
Manuela L FerreiraFaculty of Medicine and Health, Sydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-3479-0683
Christopher J GordonFaculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0003-2698-4864
Serigne N LoFaculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Kim L BennellCentre for Health, Exercise and Sports Medicine, Department of Physiotherapy, School of Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0003-4982-5639
Rachel K NelliganCentre for Health, Exercise and Sports Medicine, Department of Physiotherapy, School of Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0002-8689-6594
Rowena J FieldFaculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-1724-0321
Paulo FerreiraFaculty of Medicine and Health, Sydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAs chronic low back pain (LBP) remains one of the most pressing global health challenges, digital health emerges as an opportunity to deliver evidence-based care at scale. In this context, the My Back Exercise app has been developed to support people with LBP in self-managing their condition. This study aims to determine the effectiveness of the My Back Exercise app to improve physical function in people with chronic non-specific LBP. METHODS AND ANALYSIS: A single-blind, superiority, adaptive randomised controlled trial encompassing a multi-arm multi-stage design will be conducted and reported according to the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT), Template for the Intervention Description and Replication for telehealth (TIDieR-telehealth), and the Consolidated Standards of Reporting Trials (CONSORT) Extension for Adaptive Designs. Informed consent will be obtained from all participants. Eligible participants will be randomly assigned in a 1:1:1:1:1 ratio to either the control group, receiving education alone, or one of four intervention groups ((1) education, notifications and exercise modules; (2) education, notifications, exercise and sleep modules; (3) education, notifications, exercise and diet modules; and (4) education, notifications, exercise, sleep and diet modules) through the app. The study consists of two stages with the possibility of dropping arms for futility using pre-specified decision rules at the end of the first stage. A total of 370 participants aged 18 years or older, with chronic non-specific LBP, will be recruited Australia-wide from the general community. The primary outcome will be self-reported physical function measured by the Patient-Specific Functional Scale at 6 weeks post-randomisation. Data will be analysed using the Student's t-test or the non-parametric Mann-Whitney U test. ETHICS AND DISSEMINATION: This trial was approved by the Human Research Ethics Committee (HREC) of The University of Sydney (HREC Approval No. 2023/HE000772). The findings of this study will be disseminated via scientific publications, reports and conference presentations, and strategically disseminated to the wider community and relevant policymakers. TRIAL REGISTRATION NUMBER: Australian New Zealand Clinical Trials Registry (ACTRN12624000319572).

Indexed as

Chronic PainExercise TherapyLow Back PainMobile ApplicationsPatient Education as TopicAdultDietEquivalence Trials as TopicFemaleHumansMaleRandomized Controlled Trials as TopicSingle-Blind MethodSleepTelemedicineBack painChronic PaineHealthExerciseSpine

Identifiers

PMID40750278
PMCPMC12314989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.