Evidence map›Paper›PMID 40750249›Full record

ArticleBMJ mental health2025

Childhood trauma and recent stressors in predicting subclinical psychotic symptoms among Chinese university students in southwest China: a machine learning analysis within a gender-specific framework.

Wanjie Tang, Zijian Deng, Zeyuan Sun, Qijun Zhao, Miguel Garcia-Argibay, Kadan Anoop, Tao Hu, Shuang Xue, Natali Bozhilova, Aldo Conti and 9 more

Abstract read
In one paragraph

Article in BMJ mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Wanjie TangWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China tangwanjie2010@gmail.com jay.pan@scu.edu.cn.ORCID 0000-0002-1307-6608
Zijian DengSchool of Computing Science, Sichuan University, Chengdu, China.
Zeyuan SunDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England, UK.
Qijun ZhaoSchool of Computing Science, Sichuan University, Chengdu, China.
Miguel Garcia-ArgibaySchool of Medical Sciences, Örebro universitet, Orebro, Örebro, Sweden.ORCID 0000-0002-4811-2330
Kadan AnoopUniversity of Southampton, Southampton, England, UK.
Tao HuChengdu Normal University, Chengdu, Sichuan, China.
Shuang XueNorwegian University of Science and Technology, Trondheim, Trøndelag, Norway.
Natali BozhilovaDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England, UK.
Aldo ContiDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England, UK.
Steve LukitoDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England, UK.
Siqi WuWest China Hospital of Medicine, Chengdu, Sichuan, China.ORCID 0009-0009-1546-4696
Gang WangChengdu University, Chengdu, Sichuan, China.
Chunhan JinChongqing Jiaotong University, Chongqing, Chongqing, China.
Changjian QiuWest China Hospital of Medicine, Chengdu, Sichuan, China.
Qiaolan LiuWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Jay PanWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China tangwanjie2010@gmail.com jay.pan@scu.edu.cn.
Samuele CorteseUniversity of Southampton, Southampton, UK.ORCID 0000-0001-5877-8075
Katya RubiaDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England, UK.

Funding

National Health Institute of Care Resarch NIHR NIHR303122NIHR UK National Institute of Health Research NIHR128472NIHR UK National Institute of Health Research NIHR130077NIHR UK National Institute of Health Research NIHR203035UK Department of Health and Social Care NIHR203684
6 · The paper itself

Abstract

backgroundSubclinical psychotic symptoms (SPS) are common among college students and can lead to future mental health issues. However, it is still not clear which specific childhood trauma, stressors and health factors lead to SPSs, partly due to confounding factors and multicollinearity.

objectiveTo use machine learning to find the main predictors of SPS among university students, with special attention to gender differences.

methodsA total of 21 208 university students were surveyed regarding SPS and a wide range of stress-related factors, including academic pressure, interpersonal difficulties and abuse. Nine machine learning models were used to predict SPS. We examined the relationship between SPS and individual stressors using χ

findingsThe Extreme Gradient Boosting (XGBoost) model had the best prediction results, with an Area Under the Curve (AUC) of 0.89, and validated with external data. It also showed good calibration, and DCA indicated clear clinical benefit. Interpersonal difficulties, academic pressure and emotional abuse emerged as the strongest predictors of SPS. Gender-stratified analyses revealed that academic pressure and emotional abuse affected males more, while health issues like chest pain and menstrual pain were stronger predictors for females.

conclusionsMachine learning models effectively identified key stressors associated with SPS in university students. These findings highlight the importance of gender-sensitive approaches for the early detection and prevention of psychotic symptoms. CLINICAL IMPLICATIONS: SPSs in college students can be predicted by interpersonal difficulties, academic stress and childhood emotional abuse. This information can help mental health professionals develop better ways to prevent and address SPSs.

Indexed as

Adverse Childhood ExperiencesMachine LearningPsychotic DisordersStress, PsychologicalStudentsAdolescentAdultChinaFemaleHumansMaleSex FactorsUniversitiesYoung AdultChild & adolescent psychiatryCross-Sectional StudiesData Interpretation, StatisticalMachine Learning

Identifiers

PMID40750249
PMCPMC12314930

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.