Evidence map›Paper›PMID 40750172›Full record

ArticleJACC. Case reports2025

Recurrent Atrial Myxoma in a Patient With Carney Complex 26 Years After Heart Transplantation.

Austin Ayer, Elizabeth Silver, Antoinette Birs, Miguel Martillo Correa, Alexander Hajduczok, Victor Pretorius, Eric Adler

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Austin AyerDivision of Cardiovascular Medicine, University of California-San Diego, La Jolla, California, USA.
Elizabeth SilverDivision of Cardiovascular Medicine, University of California-San Diego, La Jolla, California, USA.
Antoinette BirsDivision of Cardiovascular Medicine, University of California-San Diego, La Jolla, California, USA.
Miguel Martillo CorreaDivision of Cardiovascular Medicine, University of California-San Diego, La Jolla, California, USA.
Alexander HajduczokDivision of Cardiovascular Medicine, University of California-San Diego, La Jolla, California, USA.
Victor PretoriusDivision of Cardiovascular and Thoracic Surgery, University of California-San Diego, La Jolla, California, USA.
Eric AdlerDivision of Cardiovascular Medicine, University of California-San Diego, La Jolla, California, USA. Electronic address: Eradler@health.ucsd.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCarney complex, a familial syndrome caused by germline PRKA1A mutation, predisposes to recurrent cardiac myxomas. In refractory cases, orthotopic heart transplantation (OHT) can be considered for assumed curative treatment of recurrent myxoma. CASE SUMMARY: We present a case of recurrent cardiac myxoma arising from residual native right atrial tissue in a woman with Carney complex 26 years after OHT for recurrent myxoma. DISCUSSION: To our knowledge, this represents the first reported case of recurrent cardiac myxoma after OHT in a patient with Carney complex. Surgical ablation of remaining atrial tissue during OHT for myxoma may reduce the risk of recurrence, and lifelong surveillance after myxoma resection in Carney complex may be indicated. TAKE-HOME MESSAGE: This case highlights a rare genetic syndrome that can cause recurrent cardiac myxomas. If OHT is performed in the context of Carney complex, attention to surgical and surveillance strategies to prevent and detect recurrence is key.

Indexed as

Carney complexheart transplantationmyxoma

Identifiers

PMID40750172
PMCPMC12441505

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.