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ArticleJACC. Case reports2025

Dual-Cavity Spontaneous Sinus of Valsalva Pseudoaneurysms: A Diagnostic and Therapeutic Challenge.

Nikolaos Ktenopoulos, Georgios Benetos, Ioannis Panagiotopoulos, Chrysavgi Simopoulou, Maria Drakopoulou, Andreas Synetos, Konstantinos Tsioufis, Konstantinos Toutouzas

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Nikolaos KtenopoulosFirst Department of Cardiology, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, Athens, Greece; Unit of Structural Heart Diseases, First Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippocration General Hospital of Athens, Greece. Electronic address: nikosktenop@gmail.com.
Georgios BenetosFirst Department of Cardiology, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, Athens, Greece; Unit of Structural Heart Diseases, First Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippocration General Hospital of Athens, Greece; CT/MRI Department, Lefkos Stavros Clinic, Athens, Greece. Electronic address: nikosktenop@gmail.com.
Ioannis PanagiotopoulosDivision of Cardiac Surgery, Hippokration General Hospital of Athens, Athens, Greece.
Chrysavgi SimopoulouFirst Department of Cardiology, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, Athens, Greece; Unit of Structural Heart Diseases, First Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippocration General Hospital of Athens, Greece.
Maria DrakopoulouFirst Department of Cardiology, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, Athens, Greece; Unit of Structural Heart Diseases, First Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippocration General Hospital of Athens, Greece.
Andreas SynetosFirst Department of Cardiology, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, Athens, Greece; Unit of Structural Heart Diseases, First Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippocration General Hospital of Athens, Greece.
Konstantinos TsioufisFirst Department of Cardiology, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, Athens, Greece; Unit of Structural Heart Diseases, First Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippocration General Hospital of Athens, Greece.
Konstantinos ToutouzasFirst Department of Cardiology, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, Athens, Greece; Unit of Structural Heart Diseases, First Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippocration General Hospital of Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSinus of Valsalva pseudoaneurysms are rare vascular anomalies with potentially life-threatening complications, and their diagnosis is challenging. CASE SUMMARY: A 75-year-old man presented with exertional dizziness and dyspnea. Imaging revealed a rare dual-cavity pseudoaneurysm of the right sinus of Valsalva, causing right ventricular outflow tract obstruction and moderate-to-severe aortic regurgitation. Multidetector computed tomography was pivotal for diagnosis and surgical planning. The patient underwent successful repair using the Bentall-de Bono technique, followed by pacemaker implantation owing to complete heart block. DISCUSSION: This case underscores the diagnostic complexity and clinical impact of spontaneous sinus of Valsalva pseudoaneurysms. The dual-cavity presentation is exceptionally rare. This case highlights the essential role of noninvasive imaging and timely surgical intervention in preventing fatal outcomes. TAKE-HOME MESSAGES: Dual-cavity sinus of Valsalva pseudoaneurysms are exceptionally rare and demand high clinical suspicion. Multidetector computed tomography is essential for diagnosis and guiding optimal surgical treatment.

Indexed as

aortaaortic valvecardiovascular diseasecomputed tomography

Identifiers

PMID40750163
PMCPMC12441543

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