ArticleJACC. Case reports2025
Computed Tomography-Derived Extracellular Volume Fraction in Non-ST-Segment Elevation Myocardial Infarction With Multivessel Disease.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
backgroundIdentifying the infarct-related artery (IRA) in non-ST-segment elevation myocardial infarction (NSTEMI) in patients with multivessel disease remains challenging. CASE SUMMARY: An 88-year-old man presented with chest pain. NSTEMI was diagnosed via electrocardiogram and elevated cardiac biomarkers. Coronary computed tomography angiography (CCTA) revealed intermediate-to-severe stenoses in the distal right coronary artery, proximal left anterior descending artery, diagonal branch, and mid-circumflex branch. CCTA-derived extracellular volume (ECV) fraction analysis demonstrated a regional elevation (31.3%) in the mid-anterolateral wall, corresponding to the diagonal branch territory. DISCUSSION: This elevated ECV fraction likely reflects acute myocardial inflammation and edema, aiding in IRA identification. Our findings suggest that computed tomography-based ECV mapping may localize acute ischemic injury, even in multivessel disease, by detecting focal edematous changes. TAKE-HOME MESSAGE: Assessment of CCTA-derived ECV fraction could enhance IRA determination in NSTEMI, potentially guiding targeted revascularization strategies and reducing diagnostic uncertainty in complex cases.
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