Evidence map›Paper›PMID 40750139›Full record

ArticleJACC. Case reports2025

Reversible Tacrolimus-Induced Dilated Hypokinetic Cardiomyopathy.

Gianluca Di Pietro, Gianluca Mennini, Antonella Ciuffreda, Lucia Ilaria Birtolo, Sara Cimino, Paola Celli, Andrea Ascione, Licia Iannello, Nicola Galea, Viviana Maestrini

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gianluca Di PietroDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Science, Sapienza University of Rome, Rome, Italy. Electronic address: gianluca.dipietro@uniroma1.it.
Gianluca MenniniDepartment of General and Specialistic Surgery, Sapienza University of Rome, Rome, Italy.
Antonella CiuffredaDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Science, Sapienza University of Rome, Rome, Italy.
Lucia Ilaria BirtoloDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Science, Sapienza University of Rome, Rome, Italy.
Sara CiminoDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Science, Sapienza University of Rome, Rome, Italy.
Paola CelliAnesthesiology and Intensive Care Unit, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy.
Andrea AscioneDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Licia IannelloDepartment of General and Specialistic Surgery, Sapienza University of Rome, Rome, Italy.
Nicola GaleaDepartment of Radiological, Oncological and Pathological Sciences, Sapienza, University of Rome, Rome, Italy.
Viviana MaestriniDepartment of Clinical, Internal, Anesthesiological and Cardiovascular Science, Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whereas calcineurin inhibitors are usually the first choice for immunosuppression, cases of tacrolimus-induced reversible heart failure have been rarely described. To add to the existing limited literature and to help clinicians, we report 2 cases of patients who developed a dilated hypokinetic cardiomyopathy early after initiating this form of immunosuppression.

Indexed as

heart failureimmunosuppressionposttransplanttacrolimus

Identifiers

PMID40750139
PMCPMC12441483

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.