Evidence map›Paper›PMID 40750064›Full record

ReviewIndian pacing and electrophysiology journal

Theory and practice of present clinical use of Quinidine in the management of cardiac arrhythmias.

Bernard Belhassen, Anat Milman

Abstract readReview
In one paragraph

Review in Indian pacing and electrophysiology journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bernard BelhassenHeart Institute, Hadassah Medical Center, Jerusalem, Israel; Grey Faculty of Medical and Health Science, Tel-Aviv University, Tel Aviv, Israel. Electronic address: bblhass@gmail.com.
Anat MilmanGrey Faculty of Medical and Health Science, Tel-Aviv University, Tel Aviv, Israel; Arrhythmia Institute, Cardiovascular Division, Shamir Medical Center (Assaf Harofeh), Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At the beginning of the last century, quinidine had been shown to be highly effective in the management of atrial fibrillation and soon after, of ventricular arrhythmias. At the end of the same century, quinidine was quickly abandoned, and its manufacturing ceased, resulting in limited accessibility across numerous countries. Paradoxically, this decline in use occurred alongside accumulating evidence supporting quinidine's therapeutic benefit in managing rare, life-threatening ventricular arrhythmias occurring in patients with no organic heart disease (Idiopathic ventricular fibrillation, Brugada syndrome, Early repolarization syndrome, Short QT syndrome, Multifocal ectopic Purkinje-related premature contractions), as well as in those with organic heart disease involving the Purkinje network (acute myocardial infarction and hypertrophic cardiomyopathy). The present review will extensively deal with all these topics.

Identifiers

PMID40750064
PMCPMC12461717

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.