Evidence map›Paper›PMID 40749896›Full record

ArticleFree radical biology & medicine2025

Phytol enhances catalase-dependent ethanol metabolism in liver independent of PPARα.

Anna Mazur, Xue Chen, Krista L Denning, Wei Xu, Logan M Lawrence, Yongke Lu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Free radical biology & medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna MazurDepartment of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, 1700 3rd Avenue, Huntington, WV, 25755, USA.
Xue ChenDepartment of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, 1700 3rd Avenue, Huntington, WV, 25755, USA.
Krista L DenningDepartment of Pathology, Joan C. Edwards School of Medicine, Marshall University, 1700 3rd Avenue, Huntington, WV, 25755, USA.
Wei XuDepartment of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, 1700 3rd Avenue, Huntington, WV, 25755, USA.
Logan M LawrenceDepartment of Pathology, Joan C. Edwards School of Medicine, Marshall University, 1700 3rd Avenue, Huntington, WV, 25755, USA.
Yongke LuDepartment of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, 1700 3rd Avenue, Huntington, WV, 25755, USA. Electronic address: luy@marshall.edu.

Funding

WV INBRE: The Inhibitor of Growth Family Member 4 (ING4) inhibits L-Type Amino Acid Transporter 1 (LAT1) expression to suppress Breast CancerP20GM103434 · NIGMS · MARSHALL UNIVERSITY · PI Travis Salisbury · 2012 to 2026
$61.1M
Nicotine and Alcoholic Liver DiseaseR01AA024723 · NIAAA · MARSHALL UNIVERSITY · PI LU, YONGKE · 2016 to 2020
$1.8M
NIAAA NIH HHS R01 AA024723NIGMS NIH HHS P20 GM103434
6 · The paper itself

Abstract

There is an interaction between peroxisomal fatty acid β-oxidation and catalase-dependent ethanol metabolism. H

Indexed as

Acyl-CoA OxidaseCatalaseEthanolLiverPhytolPPAR alphaAnimalsHydrogen PeroxideMaleMiceMice, Inbred C57BLMice, KnockoutOxidation-ReductionPeroxisomesPyrimidinesACOX1 protein, mouseAcyl-CoA OxidaseCatalaseEthanolHydrogen PeroxidePhytolpirinixic acidPPAR alphaPpara protein, mousePyrimidinesAcyl-CoA oxidaseLiverPeroxisome proliferationPPARαWY-14,643

Identifiers

PMID40749896
PMCPMC12340771

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.