Evidence map›Paper›PMID 40749055›Full record

ArticleScience advances2025

T

Changsheng Xing, Tianhao Duan, Linfeng Li, Lang Chen, Pengfei Zhang, Yang Du, Siyao Liu, Nihal Annaparthi, Shuo Wang, Chen Qian and 2 more

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Contextualizing TNature reviews. Immunology · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Changsheng XingDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.ORCID 0000-0001-6582-9037
Tianhao DuanDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.ORCID 0000-0002-1737-6114
Linfeng LiCenter for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030, USA.
Lang ChenCenter for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030, USA.
Pengfei ZhangDepartment of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.ORCID 0000-0001-7103-2016
Yang DuDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Siyao LiuDepartment of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.ORCID 0009-0000-0575-3835
Nihal AnnaparthiDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Shuo WangDepartment of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.ORCID 0000-0003-3729-8579
Chen QianDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.ORCID 0009-0006-2281-0719
Helen Y WangDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Rong-Fu WangDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.ORCID 0000-0002-8834-2763

Funding

Novel Strategies for Intervention of Inflammatory Diseases and Cancer - Research Supplement to R01-CA101795R01CA101795 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI WANG, RONGFU · 2004 to 2022
$4.6M
CD4+ T cells and neoantigens in melanoma immunotherapy.R01CA246547 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI WANG, RONGFU · 2021 to 2025
$3.1M
NCI NIH HHS R01 CA101795NCI NIH HHS R01 CA246547
6 · The paper itself

Abstract

T

Indexed as

CCAAT-Enhancer-Binding Protein-betaChemokinesColitisColonic NeoplasmsEpithelial CellsTh17 CellsAnimalsCell Line, TumorDextran SulfateDisease Models, AnimalHumansInterleukin-17MiceMice, Inbred C57BLMice, KnockoutSignal TransductionCCAAT-Enhancer-Binding Protein-betaChemokinesDextran SulfateInterleukin-17STAT3 Transcription Factor

Identifiers

PMID40749055
PMCPMC12315988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.