Evidence map›Paper›PMID 40748971›Full record

ArticlePloS one2025

Scalable quality control on processing of large diffusion-weighted and structural magnetic resonance imaging datasets.

Michael E Kim, Chenyu Gao, Nancy R Newlin, Gaurav Rudravaram, Aravind R Krishnan, Karthik Ramadass, Praitayini Kanakaraj, Kurt G Schilling, Blake E Dewey, David A Bennett and 10 more

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Characterizing Continuous and Discrete Hybrid Latent Spaces for Structural Connectomes.Proceedings of SPIE--the International Society for Optical Engineering · 2026
    Article
  9. Phenotype discovery of traumatic brain injury segmentations from heterogeneous multi-site data.Proceedings of SPIE--the International Society for Optical Engineering · 2026
    Article
  10. Assessing Open-world Foundation Models for Zero-shot Skin Segmentation in Clinical Dermatological Photographs.Proceedings of SPIE--the International Society for Optical Engineering · 2026
    Article
  11. Article
  12. Modeling a Shared Reality of Tractography through Varied Structural Imaging.Proceedings of SPIE--the International Society for Optical Engineering · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Lifespan Trajectories of Asymmetry in White Matter Tracts.bioRxiv : the preprint server for biology · 2025
    Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Michael E KimVanderbilt University, Department of Computer Science, Nashville, Tennessee, United States of America.ORCID https://orcid.org/0009-0006-3562-2688
Chenyu GaoVanderbilt University, Department of Electrical and Computer Engineering, Nashville, Tennessee, United States of America.
Nancy R NewlinVanderbilt University, Department of Computer Science, Nashville, Tennessee, United States of America.
Gaurav RudravaramVanderbilt University, Department of Electrical and Computer Engineering, Nashville, Tennessee, United States of America.
Aravind R KrishnanVanderbilt University, Department of Electrical and Computer Engineering, Nashville, Tennessee, United States of America.
Karthik RamadassVanderbilt University, Department of Computer Science, Nashville, Tennessee, United States of America.
Praitayini KanakarajVanderbilt University, Department of Computer Science, Nashville, Tennessee, United States of America.ORCID https://orcid.org/0000-0002-9979-217X
Kurt G SchillingVanderbilt University Medical Center, Department of Radiology and Radiological Sciences, Nashville, Tennessee, United States of America.
Blake E DeweyDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.ORCID https://orcid.org/0000-0003-4554-5058
David A BennettRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America.
Sid O'BryantInstitute for Translational Research, University of North Texas Health Science Center, Fort Worth, Texas, United States of America.ORCID https://orcid.org/0000-0003-0582-5266
Robert C BarberDepartment of Family Medicine, University of North Texas Health Science Center, Fort Worth, Texas, United States of America.
Derek ArcherVanderbilt University Medical Center, Vanderbilt Memory and Alzheimer's Center, Nashville, Tennessee, United States of America.
Timothy J HohmanVanderbilt University Medical Center, Vanderbilt Memory and Alzheimer's Center, Nashville, Tennessee, United States of America.
Shunxing BaoVanderbilt University, Department of Electrical and Computer Engineering, Nashville, Tennessee, United States of America.
Zhiyuan LiVanderbilt University, Department of Electrical and Computer Engineering, Nashville, Tennessee, United States of America.
Bennett A LandmanVanderbilt University, Department of Computer Science, Nashville, Tennessee, United States of America.
Nazirah Mohd KhairiVanderbilt University, Department of Electrical and Computer Engineering, Nashville, Tennessee, United States of America.ORCID https://orcid.org/0000-0003-2180-3200
Alzheimer’s Disease Neuroimaging Initiative
HABS-HD Study Team

Funding

The Health & Aging Brain Study - Health Disparities (HABS-HD)U19AG078109 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI Sid E O'Bryant · 2022 to 2026
$181.1M
Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
Health and Aging Brain among Latino Elders (HABLE-AT(N)) StudyR01AG058533 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI JOHNSON, LEIGH A, O'BRYANT, SID E · 2020 to 2025
$45.4M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
MVP Data Integration into the ADSP Phenotype Harmonization ConsortiumU24AG074855 · NIA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CUCCARO, MICHAEL L, HOHMAN, TIMOTHY J · 2021 to 2025
$37.5M
Wisconsin Registry for Alzheimer's Prevention: Sex Differences in DNA MethylationR01AG027161 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Nathaniel Ark Chin, Sterling C Johnson · 2007 to 2026
$35.6M
The Longitudinal Course of Neural Function and Amyloid in People At Risk for ADR01AG021155 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Sterling C Johnson · 2004 to 2026
$27.0M
Ultrascale Machine Learning to Empower Discovery in Alzheimers Disease BiobanksU01AG068057 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Christos Davatzikos, Heng Huang · 2020 to 2026
$20.7M
Wisconsin Registry for Alzheimer's PreventionRF1AG027161 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI JOHNSON, STERLING C · 2018 to 2018
$18.8M
TR&D3: Intrinsic Surface MappingP41EB015922 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI VAN HORN, JOHN DARRELL · 2012 to 2022
$14.1M
Health Disparities in Alzheimer's Disease and Mild Cognitive Impairment among Mexican AmericansR01AG054073 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI O'BRYANT, SID E, TOGA, ARTHUR W · 2017 to 2021
$12.6M
NCATS NIH HHS UL1 TR000445NCATS NIH HHS UL1 TR002243NIA NIH HHS K01 AG073584NIA NIH HHS R01 AG021155NIA NIH HHS R01 AG027161NIA NIH HHS R01 AG037639NIA NIH HHS R01 AG054047NIA NIH HHS R01 AG054073NIA NIH HHS R01 AG058533NIA NIH HHS R01 AG059716NIA NIH HHS R01 AG070862NIA NIH HHS R56 AG037639NIA NIH HHS RF1 AG027161NIA NIH HHS RF1 AG054047NIA NIH HHS U01 AG024904NIA NIH HHS U01 AG068057NIA NIH HHS U19 AG078109NIA NIH HHS U24 AG074855NIBIB NIH HHS K01 EB032898NIBIB NIH HHS P41 EB015922NIBIB NIH HHS R01 EB017230NIH HHS S10 OD020154NIH HHS S10 OD023680
6 · The paper itself

Abstract

Thorough quality control (QC) can be time consuming when working with large-scale medical imaging datasets, yet necessary, as poor-quality data can lead to erroneous conclusions or poorly trained machine learning models. Most efforts to reduce data QC time rely on quantitative outlier detection, which cannot capture every instance of algorithm failure. Thus, there is a need to visually inspect every output of data processing pipelines in a scalable manner. We design a QC pipeline that allows for low time cost and effort across a team setting for a large database of diffusion-weighted and structural magnetic resonance images. Our proposed method satisfies the following design criteria: 1.) a consistent way to perform and manage quality control across a team of researchers, 2.) quick visualization of preprocessed data that minimizes the effort and time spent on the QC process without compromising the condition/caliber of the QC, and 3.) a way to aggregate QC results across pipelines and datasets that can be easily shared. In addition to meeting these design criteria, we also provide a comparison experiment of our method to an automated QC method for a T1-weighted dataset of [Formula: see text] images and an inter-rater variability experiment for several processing pipelines. The experiments show mostly high agreement among raters and slight differences with the automated QC method. While researchers must spend time on robust visual QC of data, there are mechanisms by which the process can be streamlined and efficient.

Indexed as

Diffusion Magnetic Resonance ImagingImage Processing, Computer-AssistedMagnetic Resonance ImagingAlgorithmsBrainDatabases, FactualHumansQuality Control

Identifiers

PMID40748971
PMCPMC12316263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.