Evidence map›Paper›PMID 40748948›Full record

ArticlePloS one2025

The inverse relationship between dietary anthocyanidins consumption and frailty: Findings from the National Health and Nutrition Examination Survey.

Xiaofeng Zhang, Pengpeng Huang, Zhenhua Jin, Yanfei Wu

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaofeng ZhangCenter for Rehabilitation Medicine, Rehabilitation & Sports Medicine Research Institute of Zhejiang Province, Department of Rehabilitation Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Pengpeng HuangCenter for Rehabilitation Medicine, Rehabilitation & Sports Medicine Research Institute of Zhejiang Province, Department of Rehabilitation Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Zhenhua JinCenter for Rehabilitation Medicine, Rehabilitation & Sports Medicine Research Institute of Zhejiang Province, Department of Rehabilitation Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.
Yanfei WuCenter for Rehabilitation Medicine, Rehabilitation & Sports Medicine Research Institute of Zhejiang Province, Department of Rehabilitation Medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, China.ORCID https://orcid.org/0009-0003-4651-2888

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study investigates the association between dietary anthocyanidins consumption and the risk of frailty in the general adult population using data from the National Health and Nutrition Examination Survey (NHANES).

methodsA cross-sectional analysis of NHANES data was conducted, examining the relationship between dietary anthocyanidins intake and frailty risk. Dose-response relationships and subgroup analyses were performed to provide a comprehensive understanding of the associations.

resultsThe results indicate a significant inverse relationship between the consumption of specific anthocyanidin types, including malvidin and delphinidin, as well as total anthocyanidins, and the odds of frailty. Particularly, individuals aged 41-60 years and males exhibited a notable protective effect of anthocyanidins against frailty. Dose-response analyses revealed a U-shaped relationship between total anthocyanidins intake and frailty risk, with an optimal consumption level of 33.322 mg per day.

conclusionThis pioneering study emphasizes the potential protective role of dietary anthocyanidins in mitigating frailty, especially among middle-aged individuals and males.

Indexed as

AnthocyaninsDietFrailtyAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysUnited StatesAnthocyanins

Identifiers

PMID40748948
PMCPMC12316302

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