Evidence map›Paper›PMID 40748497›Full record

ArticleArchives of women's mental health2025

Maternal psychiatric admissions and Child developmental delays: A nationwide cohort study.

Yonatan Bilu, Guy Amit, Noa Gueron-Sela, Liat Azani, Rinat Yoffe, Mark Weiser, Vered Bar

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Article in Archives of women's mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yonatan BiluKI Research Institute, Kfar Malal, Israel. yonatan@kinstitute.org.il.ORCID 0000-0001-9119-7889
Guy AmitKI Research Institute, Kfar Malal, Israel.
Noa Gueron-SelaDepartment of Psychology, Ben Gurion University of the Negev, Beer Sheva, Israel.
Liat AzaniTIMNA Initiative - Big Data Platform, Ministry of Health, Jerusalem, Israel.
Rinat YoffeDepartment of Information and Evaluation, Ministry of Health, Jerusalem, Israel.
Mark WeiserThe Drora and Pinchas Zachai Division of Psychiatry, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Hashomer, Israel.
Vered BarChava Center, The Drora and Pinchas Zachai Division of Psychiatry, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Hashomer, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeChildren of mothers experiencing mental illness are known to exhibit elevated rates of developmental delays. However, there is little evidence-based research on the impact of perinatal psychiatric admissions. Here we aim to quantify the association between maternal mental illness that leads to admission, and the likelihood of child developmental delay. In addition, we aim to understand the association between the timing of admission, the maternal diagnosis and the developmental domain in which delays manifest.

methodsRetrospective cohort study of data from well-child visits of 634,918 term-born children assessed between 2016 and 2022 at the ages of 1 to 36 months. Likelihood of failure in milestone attainment was modelled based on maternal psychiatric information available through the national registry, and adjusted for demographic and birth data from the Israeli national program of Maternal Child Health Clinics. Secondary analyses examined stratification by maternal diagnosis, timing of admission and developmental domain, as well as comparison to the association between the likelihood of child developmental delay and maternal high scores on the Edinburgh Postnatal Depression Scale.

resultsMaternal mental illness that leads to psychiatric admission was associated with an increased odds ratio for child developmental delay (OR ~ 1.7). Higher odds ratio was associated with psychotic disorders diagnoses, multiple admissions and admissions between birth and child assessment. Nonetheless, increased odds were suggested also when first admission occurred after child assessment. In addition, increased odds were more evident when children were assessed at an older age.

conclusionsChildren of mothers experiencing mental illness exhibit higher rates of developmental delays, especially when mothers are admitted. Identifying and supporting high-risk dyads during the peripartum period is therefore critical for both mother and child.

Indexed as

Child of Impaired ParentsDevelopmental DisabilitiesHospitalizationMental DisordersMothersAdultChild, PreschoolCohort StudiesFemaleHumansInfantIsraelMalePregnancyRetrospective StudiesChild developmentChild developmental delayMaternal mental healthMental Health EpidemiologyPerinatal mental health

Identifiers

PMID40748497
PMCPMC12702798

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