ReviewHistochemistry and cell biology2025
The ILK-PINCH-parvin complex: a conserved primary adhesome regulating biological processes.
Review in Histochemistry and cell biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Signalling networks orchestrating the development of Drosophila indirect flight muscles.Histochemistry and cell biology · 2026Review
- Integrin-Linked Kinase Plays an Active Role in the Regulation of Endothelial Senescence.Cells · 2026Article
- Identification and Validation of 3-Cyano-Quinoline Ligands Targeting Integrin-Linked Kinase (ILK).Journal of medicinal chemistry · 2026Article
- Nanotopography-Mediated Mechanotransduction Enhances hBMSCs Adhesion on TiOJournal of functional biomaterials · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intracellularly expressed integrin associated proteins (IAPs) play pivotal role in facilitating cellular adhesion and survival. The integrin linked kinase (ILK)-PINCH-parvin (IPP) complex regulates cell-matrix interactions crucial for tissue development and homeostasis by functioning as an adapter between integrin and actin cytoskeleton. This review provides a compiled structural and functional insight into the IPP complex and its interacting partners, highlighting its conservation and signalling pathway, addressing a cross-talk across its homologues. Finally, the study sheds light on the association of the complex members with biological processes and disease progression, thus potentiating further exploration of the IPP complex within the integrin signalling pathway.
Indexed as
Identifiers
40748480What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.