SynthesisAdvances in therapy2025
Clinical and Humanistic Burden of Adult Obesity in Asia-Pacific: A Systematic Literature Review.
Synthesis in Advances in therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Effect of Tirzepatide on Health-Related Quality of Life in Japanese Patients With Obesity Disease: Patient-Reported Outcomes From the SURMOUNT-J Study.Diabetes, obesity & metabolism · 2026Trial
- The impact of metabolic syndrome and triglyceride-glucose index on the risk of in-stent restenosis after percutaneous coronary intervention: a retrospective study.Frontiers in cardiovascular medicine · 2026Article
- Association Between Body Fat Percentage and Endometriosis Severity Based on American Association of Gynecologic Laparoscopists 2021 Endometriosis Classification.International journal of women's health · 2026Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionObesity continues to be an increasing global health concern. However, the burden of obesity within the Asia-Pacific (APAC) region is less well defined relative to Western countries.
methodsA systematic literature review was conducted to characterise disease burden in people with obesity within the APAC region (defined as body mass index of ≥ 30 kg/m
resultsComplications were reported at significantly higher rates in people with obesity compared to people with a normal weight. Diabetes, hypertension, dyslipidaemia, and cardiovascular diseases were the most frequently reported obesity-related complications, and rates among people with obesity were as high as 57%, 72%, 65%, and 23% respectively. Low scores on patient-reported outcome measures indicated reduced health-related quality of life (HRQoL) among people with obesity, with lower HRQoL in those with a higher obesity class. Psychological distress was also elevated in people with obesity which persisted despite treatment.
conclusionDespite variation in the definition of obesity across countries in the APAC region, obesity was consistently associated with notable presence of related metabolic, cardiovascular, and psychological complications. Obesity substantially impacts psychosocial and emotional wellbeing and is associated with a reduced HRQoL in people with obesity. This highlights the need to proactively recognise and manage obesity as a chronic relapsing disease to improve the health of people with obesity. Further research is warranted to address identified evidence gaps in the APAC region.
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