Evidence map›Paper›PMID 40748395›Full record

ArticleWorld journal of urology2025

Posterior urethroplasty for pelvic fracture urethral injuries: risk factors for recurrence and complications.

Natalia Plamadeala, Marjan Waterloos, Mieke Waterschoot, Nicolaas Lumen

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Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Natalia PlamadealaDepartment of Urology, Ghent University Hospital, Ghent, Belgium. n.plamadeala@unito.it.ORCID http://orcid.org/0009-0004-8781-1216
Marjan WaterloosDepartment of Urology, Ghent University Hospital, Ghent, Belgium.ORCID http://orcid.org/0000-0003-1642-7263
Mieke WaterschootDepartment of Urology, Ghent University Hospital, Ghent, Belgium.ORCID http://orcid.org/0000-0002-9510-611X
Nicolaas LumenDepartment of Urology, Ghent University Hospital, Ghent, Belgium.ORCID http://orcid.org/0000-0003-1242-3644

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSurgical reconstruction for posterior urethral injuries associated with pelvic fractures (PFUI) is complex. Perineal posterior urethroplasty via excision and primary anastomosis (EPA) is the standard treatment. This study evaluates risk factors for stenosis recurrence after primary EPA and analyzes predictors of postoperative complications.

methodsA retrospective analysis was conducted on male patients who underwent primary posterior EPA for PFUI at Ghent University Hospital (2001-2024). The primary outcome was stenosis recurrence at 1-, 2-, and 10-year follow-up, defined as urethral narrowing causing obstructive symptoms and requiring intervention. Demographic data, prior urethral manipulation, surgical techniques, 90-day complications (Clavien-Dindo), and functional outcomes were analyzed. Univariate and multivariate coxregression analyses were performed using IBM SPSS Statistics v. 29.0.2.0.

resultsAmong 70 patients, 75.5% underwent transecting EPA. After a median follow-up of 130 months (IQR 78.5-178.5), stenosis recurrence occurred in 15.8% at a median of 3 months (IQR 2.0-5.0). The 1-, 2-, and 10-year recurrence-free survival rates were 85.4%, 83.8%, and 83.8%, respectively. In multivariate analysis, postoperative complications (HR = 4.85, p = 0.007) and persistent extravasation (HR = 6.36, p = 0.006) significantly increased recurrence risk. Postoperative complications (21.4%) were all low-grade and managed conservatively. Erectile function was impaired in 97.9% due to trauma, with 12.2% improving postoperatively. De novo urinary incontinence occurred in 6.6%.

conclusionsPosterior urethroplasty demonstrates a high long-term success rate in patients with PFUI. Postoperative complications and persistent urinary leakage significantly increase the risk of surgical failure, highlighting the need for rigorous follow-up. The non-transecting technique, when possible, does not negatively impact outcomes.

Indexed as

Fractures, BonePelvic BonesPlastic Surgery ProceduresPostoperative ComplicationsUrethraUrethral StrictureUrologic Surgical Procedures, MaleAdultAgedHumansMaleMiddle AgedRecurrenceRetrospective StudiesRisk FactorsPelvic fracture urethral injuryPosterior urethroplastyStenosis recurrenceUrethral reconstructionUrethroplasty complications

Identifiers

PMID40748395
PMCPMC12316716

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.