Evidence map›Paper›PMID 40748351›Full record

ArticleAlcohol, clinical & experimental research2025

Knowledge as prevention: A cost-effective intervention to reduce prenatal alcohol exposure.

Orlagh Keating, Ruth H Brown, Stewart McDougall, Renate Kuenssberg, Suzanne O'Rourke

Abstract read
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Article in Alcohol, clinical & experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Orlagh KeatingClinical and Health Psychology Department, University of Edinburgh, Edinburgh, UK.
Ruth H BrownClinical and Health Psychology Department, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-1713-3585
Stewart McDougallClinical and Health Psychology Department, University of Edinburgh, Edinburgh, UK.
Renate KuenssbergNHS Fife Psychology Department, Lynebank Hospital, Dunfermline, UK.
Suzanne O'RourkeClinical and Health Psychology Department, University of Edinburgh, Edinburgh, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrenatal alcohol exposure (PAE) remains high despite international guidelines recommending alcohol abstinence during pregnancy. This poses a significant public health concern, as PAE is known to have harmful effects on fetal development and is the cause of fetal alcohol spectrum disorder (FASD). Enhancing knowledge and shifting attitudes toward PAE may help reduce its occurrence, but evidence remains limited. This study examined the impact of an educational intervention on knowledge and attitudes toward PAE among pregnant and recently pregnant women.

methodsA total of 1536 UK-based women aged 19-50 years (M = 33.3 years) participated in an anonymous online questionnaire with an embedded intervention consisting of an existing information leaflet, "Alcohol and Pregnancy," developed by the Royal College of Obstetricians and Gynaecologists. Participants completed pre- and postintervention evaluations of their knowledge and attitudes toward PAE.

resultsThe intervention led to significantly increased negative attitudes toward PAE (z = -9.67, p < 0.001, r = 0.29) and improved knowledge of its associated risks (z = -21.16, p < 0.001, r = 0.65). Regression analysis indicated that participants with alcohol-exposed pregnancies, and with more positive initial attitudes and lower baseline knowledge of PAE-associated risks, experienced the greatest changes postintervention (F [11, 1021] = 25.42, p < 0.001, adj. R

conclusionThese findings highlight the effectiveness of low-cost, self-administered educational interventions in enhancing knowledge of risks and discouraging alcohol use during pregnancy. Implementation of such interventions in community, clinical, and online settings is recommended to reduce prenatal alcohol consumption.

Indexed as

Alcohol DrinkingCost-Benefit AnalysisFetal Alcohol Spectrum DisordersHealth Knowledge, Attitudes, PracticePrenatal Exposure Delayed EffectsAdultFemaleHumansMiddle AgedPregnancySurveys and QuestionnairesYoung Adultalcoholattitudes toward drinkingeducational interventionknowledgepregnancy

Identifiers

PMID40748351
PMCPMC12365574

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.