Trial reportJournal of burn care & research : official publication of the American Burn Association2026
Within-Patient, Evaluator-Blinded, Randomized Controlled Clinical Trial to Assess the Efficacy of Gel Sheets in the Treatment of Hypertrophic Scar in Adult Burn Survivors.
Trial report in Journal of burn care & research : official publication of the American Burn Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Rehabilitation Evaluation and Treatment for Skin Graft Complications of the Genitalia.Journal of burn care & research : official publication of the American Burn Association · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Gel sheets have been used to treat hypertrophic scars (HSc) since the 1980s, though evidence for their efficacy-especially for burn-related HSc-is limited. This study conducted a randomized, evaluator-blinded trial to assess gel sheets on established burn HSc compared to intra-individual patient-matched control scars receiving usual care. Thirty-six adult burn survivors with 2 similar scars (based on ultrasound thickness > 2.034 mm and erythema index > 300) were enrolled. One scar per person was randomly assigned to receive gel sheets plus usual care, while the other received usual care only, over a 3-month period. Objective measures (thickness, elasticity, erythema, transepidermal water loss [TEWL], and melanin) were taken at baseline, monthly, and 1-month posttreatment. Itch and pain were self-reported, and adherence tracked monthly. An analysis of covariance (ANCOVA) after 3 months of treatment, and at 1-month posttreatment follow-up, controlling for pretreatment values, showed no significant difference between groups for thickness, elasticity, erythema, TEWL, melanin or itch intensity. However, ANCOVA revealed a significant increase in elasticity in the treated scars when only participants who wore the gel sheet over 16 h a day were analyzed. Comparisons of pretreatment to 3 months of all participants, using paired t-tests, showed a significant decrease in thickness and TEWL, and an increase in elasticity in both groups, but no significant change in erythema or melanin of either site. In conclusion, scar thickness, elasticity, and TEWL improved over time in both groups, but there was no significant between-group difference. However, gel sheets may enhance elasticity if worn over 16 h daily.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.