Evidence map›Paper›PMID 40747744›Full record

ArticleCancer medicine2025

Early Cancer Survivorship Distress Trajectories Associated With Socioeconomic Status and Age: Findings From a Multicenter Prospective Study.

Anja Mehnert-Theuerkauf, Ute Goerling, Tanja Zimmermann, Jochen Ernst, Myriel Hermann, Beate Hornemann, Ulrich Keilholz, Florian Lordick, Olaf von dem Knesebeck, David Kissane and 2 more

Registry-linked trialAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04620564 (Longitudinal Analysis of Mental Disorders, Psychosocial Distress and Psycho-oncological Care Needs of Patients and Their Relatives Stratified by Biopsychosocial Factors), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04620564 unknown statusnot on this map

Longitudinal Analysis of Mental Disorders, Psychosocial Distress and Psycho-oncological Care Needs of Patients and Their Relatives Stratified by Biopsychosocial Factors (LUPE)

TypeobservationalSponsorUniversity of LeipzigRan2020 to 2023Enrolled2,000ConditionsNeoplasm Malignant
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Anja Mehnert-TheuerkaufDepartment of Medical Psychology and Medical Sociology, Comprehensive Cancer Center Central Germany (CCCG), University Medical Center Leipzig, Leipzig, Germany.ORCID https://orcid.org/0000-0002-6872-9805
Ute GoerlingCorporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charité Comprehensive Cancer Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0001-8157-3836
Tanja ZimmermannDepartment of Psychosomatic Medicine and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0002-5069-7278
Jochen ErnstDepartment of Medical Psychology and Medical Sociology, Comprehensive Cancer Center Central Germany (CCCG), University Medical Center Leipzig, Leipzig, Germany.ORCID https://orcid.org/0000-0002-2374-3232
Myriel HermannCorporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charité Comprehensive Cancer Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0003-3579-4085
Beate HornemannNational Center for Tumor Diseases Dresden (NCT/UCC), University Hospital Carl Gustav Carus Dresden, Dresden, Germany.ORCID https://orcid.org/0009-0005-4916-7500
Ulrich KeilholzCorporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charité Comprehensive Cancer Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0001-6773-9406
Florian LordickDepartment of Medicine II (Oncology, Gastroenterology, Hepatology, and Pulmonology), Comprehensive Cancer Center Central Germany (CCCG), University of Leipzig Medical Center, Leipzig, Germany.ORCID https://orcid.org/0000-0001-8591-9339
Olaf von dem KnesebeckInstitute of Medical Sociology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID https://orcid.org/0000-0001-6310-5879
David KissaneSchool of Medicine, University of Notre Dame Australia, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-5930-4573
Anne-Kathrin KöditzDepartment of Medical Psychology and Medical Sociology, Comprehensive Cancer Center Central Germany (CCCG), University Medical Center Leipzig, Leipzig, Germany.ORCID https://orcid.org/0009-0006-8432-5217
Franziska SpringerDepartment of Medical Psychology and Medical Sociology, Comprehensive Cancer Center Central Germany (CCCG), University Medical Center Leipzig, Leipzig, Germany.ORCID https://orcid.org/0000-0002-1586-4050

Funding

Charité Comprehensive Cancer Center BerlinDepartment of Medical Psychology and Medical Sociology, University Medical Center of LeipzigDepartment of Psychosomatic Medicine and Psychotherapy, Hannover Medical SchoolGerman Cancer Aid Foundation (Deutsche Krebshilfe, DKH) 70113544German Cancer Aid Foundation (Deutsche Krebshilfe, DKH) 70113611German Cancer Aid Foundation (Deutsche Krebshilfe, DKH) 70113613Open Access Publishing Fund of Leipzig University
6 · The paper itself

Abstract

backgroundSocioeconomic status' (SES) impact on distress during cancer survivorship has been insufficiently studied, although the consequences of low SES can be cumulative and adversely impact a person's ability to access resources required for improved health and quality of life. PATIENTS AND

methodsWe conducted a prospective study involving newly diagnosed patients within 2 months of diagnosis (t1), and at 6-, 12-, and 18-month follow-up (t2-t4) using the Distress Thermometer (DT). Generalized Linear Mixed Models (GLMM) were used to test for changes in distress over time, with fixed effects of time, SES, and age.

resultsOut of 1702 eligible patients, 965 completed the baseline DT (53% men, 60.5 years); 779, 681, and 626 participated at follow-ups. Out of 554 completers, 9% were chronically distressed, while 40.8% were never distressed. Distress decreased in 21.3%, increased in 11.0%, and 17.8% fluctuated over time. Low-SES patients consistently had the highest rates of distress. Distress scores and the frequency of distress (DT ≥ 5) decreased over time in all SES and age groups: For DT mean scores, GLMM revealed a significant effect of time (χ

conclusionEffective psychosocial interventions require a customized approach to decrease distress in vulnerable groups.

trial registrationThis study was registered in the International Clinical Trials Registry (NCT04620564, https://clinicaltrials.gov/).

Indexed as

Cancer SurvivorsNeoplasmsPsychological DistressSocial ClassStress, PsychologicalSurvivorshipAdultAgedAge FactorsFemaleHumansMaleMiddle AgedProspective StudiesQuality of Lifeagecancer survivorshipdistresslongitudinal studypsycho‐oncologysocioeconomic status

Identifiers

PMID40747744
PMCPMC12314646

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.